p-Chloro-α,β-dimethyl-N-propylbenzeneethanamine

Base Information

• Chemical Name: p-Chloro-α,β-dimethyl-N-propylbenzeneethanamine
• CAS No.: 20110-30-9
• Molecular Formula: C₁₃H₂₀ClN
• Molecular Weight: 225.762
• Mol file: 20110-30-9.mol

Synonyms:[2-(4-Chloro-phenyl)-1-methyl-propyl]-propyl-amine;

Chemical Property of p-Chloro-α,β-dimethyl-N-propylbenzeneethanamine

Chemical Property:

• Vapor Pressure: 0.00146mmHg at 25°C
• Boiling Point: 296.1°C at 760 mmHg
• PKA: 10.15±0.29(Predicted)
• Flash Point: 132.9°C
• PSA: 12.03000
• Density: 0.995g/cm³
• LogP: 4.22250

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-Chloro-α,β-dimethyl-N-propylbenzeneethanamine

There total 4 articles about p-Chloro-α,β-dimethyl-N-propylbenzeneethanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-chloro-4-(2-nitropropenyl)benzene (710-20-3) → N-Propyl-2-(p-chlorphenyl)-3-butylamin (20110-30-9)

Guidance literature:

Multi-step reaction with 3 steps

1: Fe, FeCl₃, aq. HCl / 1 h / Heating

2: (i) NaOiPr, iPrOH, (ii) /BRN= 969135/

3: Al, HgCl₂ / ethanol; H₂O / 3 h / Heating

With hydrogenchloride; iron(III) chloride; iron; aluminium; mercury dichloride; In ethanol; water;

Reference yield:

4-chlorobenzaldehyde (104-88-1) → N-Propyl-2-(p-chlorphenyl)-3-butylamin (20110-30-9)

Guidance literature:

Multi-step reaction with 4 steps

1: NH₄OAc / acetic acid / 3 h / Heating

2: Fe, FeCl₃, aq. HCl / 1 h / Heating

3: (i) NaOiPr, iPrOH, (ii) /BRN= 969135/

4: Al, HgCl₂ / ethanol; H₂O / 3 h / Heating

With hydrogenchloride; ammonium acetate; iron(III) chloride; iron; aluminium; mercury dichloride; In ethanol; water; acetic acid;

Reference yield:

1-(4-chlorophenyl)propan-2-one (5586-88-9) → N-Propyl-2-(p-chlorphenyl)-3-butylamin (20110-30-9)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) NaOiPr, iPrOH, (ii) /BRN= 969135/

2: Al, HgCl₂ / ethanol; H₂O / 3 h / Heating

With aluminium; mercury dichloride; In ethanol; water;

upstream raw materials:

propylamine

(+/-)-3-(p-chlorophenyl)butan-2-one

1-chloro-4-(2-nitropropenyl)benzene

4-chlorobenzaldehyde