Ethynamine, N,N-diethyl-2-phenyl-

Base Information

• Chemical Name: Ethynamine, N,N-diethyl-2-phenyl-
• CAS No.: 4231-26-9
• Molecular Formula: C12H15N
• Molecular Weight: 173.258
• Mol file: 4231-26-9.mol

Synonyms:

Chemical Property of Ethynamine, N,N-diethyl-2-phenyl-

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Ethynamine, N,N-diethyl-2-phenyl-

There total 6 articles about Ethynamine, N,N-diethyl-2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2',2'-difluorostyrene (405-42-5) + lithium diethylamide (816-43-3) → diethylamino-1 phenyl-2 acetylene (4231-26-9)

Guidance literature:

In diethyl ether; -78 deg C, 20 min, r.t., 2 h;

DOI:10.1246/cl.1980.935

Reference yield:

1.2-Dichlor-1--2-phenyl-aethylen (716-58-5) → diethylamino-1 phenyl-2 acetylene (4231-26-9)

Guidance literature:

With n-butyllithium; In diethyl ether; at -10 - 20 ℃;

Reference yield:

diethylamine (109-89-7) + phenylacetylene (536-74-3) → diethylamino-1 phenyl-2 acetylene (4231-26-9)

Guidance literature:

With oxygen; copper(II) bis(trifluoromethanesulfonate); In toluene; at 5 ℃; for 1h;

DOI:10.1021/jo5029198

upstream raw materials:

2',2'-difluorostyrene

lithium diethylamide

1.2-Dichlor-1--2-phenyl-aethylen

dichloroethyne

Downstream raw materials:

N¹,N¹-diisopropyl-N²-(4-methylbenzenesulfonyl)-2-phenylacetamidine

2-Phenyl-pentadien-(3.4)-saeure-diethylamid

2-Phenyl-3-diaethylamino-4,4-diphenyl-cyclobuten-⁽²⁾-on

<2-Phenyl-1-diaethylamino-aethyliden>-cyanessigsaeure-aethylester

Refernces

• 1、 Hayashi, Sei-ichi,Nakai, Takeshi,Ishikawa, Nobuo. "DEFLUORINATIVE COUPLING REACTIONS OF gem-DIFLUOROOLEFINS WITH ORGANOLITHIUM REAGENTS. NOVEL, FACILE METHODS FOR CHAIN ELONGATIONS OF ALDEHYDES LEADING TO AMIDES, ACETYLENES, AND KETONES". . p. 935 - 938. Retrieved 2007/10/02.