1-bromo-4-nitronaphthalene

Base Information

• Chemical Name: 1-bromo-4-nitronaphthalene
• CAS No.: 4236-05-9
• Molecular Formula: C10H6BrNO2
• Molecular Weight: 252.067
• Hs Code.: 2904909090
• Mol file: 4236-05-9.mol

Synonyms:1-Bromo-4-nitronaphthalin;4-bromo-1-nitronaphthalene;4-bromo-1-decylbenzene;4-decyl-1-bromobenzene;Naphthalene, 1-bromo-4-nitro-;4-Brom-1-nitronaphthalin;Benzene,1-bromo-4-decyl;1-Brom-4-nitro-naphthalin;1-bromo-4-n-decyl benzene;p-decylphenylbromide;1-bromo-4-nitro-naphthalene;4-Decylbromobenzene;

Chemical Property of 1-bromo-4-nitronaphthalene

Chemical Property:

• Melting Point: 87-88 °C
• Boiling Point: 355.9±17.0 °C(Predicted)
• PSA: 45.82000
• Density: 1.662±0.06 g/cm3(Predicted)
• LogP: 4.03370
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-4-nitronaphthalene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 1-Bromo-4-nitronaphthalene is a useful reagent for organic synthesis.

Technology Process of 1-bromo-4-nitronaphthalene

There total 13 articles about 1-bromo-4-nitronaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

1-amino-4-nitronaphthalene (776-34-1) → 4-bromo-1-nitronaphthalene (4236-05-9)

Guidance literature:

With tert.-butylnitrite; camphor-10-sulfonic acid; tetrabutylammomium bromide; copper(ll) bromide; In acetonitrile; at 60 ℃; for 24h;

DOI:10.1021/acs.jmedchem.9b00723

Reference yield: 79.0%

1-bromo-4-(dihydroxyboryl)naphthalene (145965-14-6) → 4-bromo-1-nitronaphthalene (4236-05-9)

Guidance literature:

With dipotassium peroxodisulfate; bismuth (III) nitrate pentahydrate; In benzene; at 70 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol300325t

Reference yield:

1-Nitronaphthalene (86-57-7) → 4-bromo-1-nitronaphthalene (4236-05-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; potassium hydroxide / methanol; ethanol / 2 h / 60 °C

2: tert.-butylnitrite; copper(ll) bromide; tetrabutylammomium bromide; camphor-10-sulfonic acid / acetonitrile / 24 h / 60 °C

With tert.-butylnitrite; camphor-10-sulfonic acid; hydroxylamine hydrochloride; tetrabutylammomium bromide; potassium hydroxide; copper(ll) bromide; In methanol; ethanol; acetonitrile;

DOI:10.1021/acs.jmedchem.9b00723

upstream raw materials:

1-Bromonaphthalene

1-amino-4-nitronaphthalene

1-bromo-4-nitro-[2]naphthylamine

4-Bromo-1-naphthylamine

Downstream raw materials:

1,4-dibromonaphthalene

4-Bromo-1-naphthylamine

N-(4-nitro-1-naphthyl) benzamide

Refernces

• 1、 Manna, Srimanta,Maity, Soham,Rana, Sujoy,Agasti, Soumitra,Maiti, Debabrata. "Ipso-nitration of arylboronic acids with bismuth nitrate and perdisulfate". supporting information; experimental part. p. 1736 - 1739. Retrieved 2012/05/20.