5-(2-Bromoethyl)hydantoin

Base Information

• Chemical Name: 5-(2-Bromoethyl)hydantoin
• CAS No.: 7471-52-5
• Molecular Formula: C5H7BrN2O2
• Molecular Weight: 207.027
• Mol file: 7471-52-5.mol

Synonyms:5-(2-Brom-aethyl)-imidazolidin-2,4-dion;5-(2-Bromoethyl)hydantoin;5-(2-bromo-ethyl)-imidazolidine-2,4-dione;

Chemical Property of 5-(2-Bromoethyl)hydantoin

Chemical Property:

• Melting Point: 139-141 °C(Solv: water (7732-18-5))
• PKA: 8.69±0.10(Predicted)
• PSA: 58.20000
• Density: 1.662g/cm³
• LogP: 0.63700

Purity/Quality:

99% ^*data from raw suppliers

5-(2-Bromoethyl)hydantoin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(2-Bromoethyl)hydantoin

There total 9 articles about 5-(2-Bromoethyl)hydantoin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-Homoserine (1927-25-9,119736-88-8) → 5-(β-bromoethyl)hydantoin (7471-52-5)

Guidance literature:

With potassium cyanate; water; anschliessend mit wss.HBr;

DOI:10.1021/ja01228a050 DOI:10.1021/ja01154a601

Reference yield:

→ 5-(β-bromoethyl)hydantoin (7471-52-5)

Guidance literature:

With hydrogen bromide; at 120 ℃;

DOI:10.1021/ja01228a050

Reference yield:

→ 5-(β-bromoethyl)hydantoin (7471-52-5)

Guidance literature:

beim aufeinanderfolgenden Behandeln mit wss.K₂CO₃, mit wss. Kaliumcyanat und mit wss.HBr;

DOI:10.1021/ja01562a050

upstream raw materials:

DL-Homoserine

hydrogen bromide

(2-oxotetrahydrofuran-3-yl)urea

5-hydroxyethyl hydantoin

Downstream raw materials:

5-(2-benzylselanyl-ethyl)-imidazolidine-2,4-dione

5-<β-(phenyltelluro)ethyl>hydantoin

5-[2-(methylthio)ethyl]imidazolidine-2,4-dione

Refernces

• 1、 Andaloussi, Mounir,Lindh, Martin,Bj?rkelid, Christofer,Suresh, Surisetti,Wieckowska, Anna,Iyer, Harini,Karlén, Anders,Larhed, Mats. "Substitution of the phosphonic acid and hydroxamic acid functionalities of the DXR inhibitor FR900098: An attempt to improve the activity against Mycobacterium tuberculosis". scheme or table. p. 5403 - 5407. Retrieved 2011/10/12.
• 2、 -. " 123m Te-Labeled biochemicals and method of preparation". . . Retrieved 2008/06/13.