9-Diphenylmethyl-fluorene

Base Information

• Chemical Name: 9-Diphenylmethyl-fluorene
• CAS No.: 4425-68-7
• Molecular Formula: C26H20
• Molecular Weight: 332.445
• DSSTox Substance ID: DTXSID001306821
• Mol file: 4425-68-7.mol

Synonyms:9-diphenylmethyl-fluorene;9-benzhydryl-9H-fluorene;9-(Diphenylmethyl)-9H-fluorene;DTXSID001306821;AKOS015968261;4425-68-7

Chemical Property of 9-Diphenylmethyl-fluorene

Chemical Property:

• XLogP3: 6.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 3
• Exact Mass: 332.156500638
• Heavy Atom Count: 26
• Complexity: 401

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(C2C3=CC=CC=C3C4=CC=CC=C24)C5=CC=CC=C5

Technology Process of 9-Diphenylmethyl-fluorene

There total 24 articles about 9-Diphenylmethyl-fluorene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

benzophenone (119-61-9) + 9H-fluorene (86-73-7) + 1,1-Diphenylmethanol (91-01-0) → 9-(diphenylmethyl)fluorene (4425-68-7)

Guidance literature:

With cesiumhydroxide monohydrate; In toluene; at 160 ℃; for 24h; Reagent/catalyst; Sealed tube; Inert atmosphere; Green chemistry;

DOI:10.1039/c6gc02518h

Reference yield: 66.0%

9H-fluorene (86-73-7) + 1,1-Diphenylmethanol (91-01-0) → 9-benzhydrylidenefluorene (4709-68-6) + 9-(diphenylmethyl)fluorene (4425-68-7)

Guidance literature:

With [ruthenium(II)(η⁶-1-methyl-4-isopropyl-benzene)(chloride)(μ-chloride)]₂; potassium tert-butylate; In toluene; at 140 ℃; for 48h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.9b02913

Reference yield: 56.0%

3',3'-diphenyl-spiro[fluoren-9,2'-oxirane] (132869-70-6) → 9H-fluorene (86-73-7) + 9-benzhydrylidenefluorene (4709-68-6) + 9-(diphenylmethyl)fluorene (4425-68-7) + (9H-fluoren-9-yl)-diphenylmethanol (87823-45-8)

Guidance literature:

With sodium; In various solvent(s); Product distribution; Mechanism; other solvents, other alkali metals;

upstream raw materials:

diethyl ether

9-chlorofluorene

benzhydryl sodium

9-benzhydrylidenefluorene

Refernces

• 1、 Shaikh, Moseen A.,Agalave, Sandip G.,Ubale, Akash S.,Gnanaprakasam, Boopathy. "Ligand-Free Ru-Catalyzed Direct sp3 C-H Alkylation of Fluorene Using Alcohols". . p. 2277 - 2290. Retrieved 2020/02/04.
• 2、 Steffensmeier, Eric,Swann, Matthew T.,Nicholas, Kenneth M.. "Mechanistic Features of the Oxidation-Reductive Coupling of Alcohols Catalyzed by Oxo-Vanadium Complexes". supporting information. p. 844 - 854. Retrieved 2019/01/04.