1,1-diisopropylguanidine sulfate

Base Information

• Chemical Name: 1,1-diisopropylguanidine sulfate
• CAS No.: 44873-60-1
• Molecular Formula: C7H17N3
• Molecular Weight: 241.30800
• Mol file: 44873-60-1.mol

Synonyms:

Chemical Property of 1,1-diisopropylguanidine sulfate

Chemical Property:

• PSA: 136.09000
• LogP: 2.22670

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1-diisopropylguanidine sulfate

There total 5 articles about 1,1-diisopropylguanidine sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N,N'-bis(tert-butoxycarbonyl)-N,N-diisopropylguanidine (153114-33-1) → N,N-Diisopropyl-guanidin (44873-60-1)

Guidance literature:

With trifluoroacetic acid;

DOI:10.1016/S0040-4039(00)61537-X

Reference yield:

diisopropylamine (108-18-9) → N,N-Diisopropyl-guanidin (44873-60-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: polymer-supported carbodiimide / CH₂Cl₂ / 16 h / 20 °C

1.2: tris(2-aminoethyl)amine, polymer-bound / CH₂Cl₂ / 16 h / 20 °C

2.1: trifluoroacetic acid / CH₂Cl₂ / 6 h / 20 °C

With polymer-supported carbodiimide; trifluoroacetic acid; In dichloromethane;

DOI:10.1016/S0040-4039(02)01390-4

Reference yield:

diisopropylamine (108-18-9) → N,N-Diisopropyl-guanidin (44873-60-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / Et₃N, HgCl₂ / dimethylformamide / 0.5 h / 0 °C

2: CF₃COOH

With triethylamine; trifluoroacetic acid; mercury dichloride; In N,N-dimethyl-formamide;

DOI:10.1016/S0040-4039(00)61537-X

upstream raw materials:

CYANAMID

diisopropylamine hydrochloride

diisopropylamine

N,N'-bis(tert-butoxycarbonyl)-N,N-diisopropylguanidine

Refernces

• 1、 Kim, Kyoung Soon,Qian, Ligang. "Improved Method for the Preparation of Guanidines". . p. 7677 - 7680. Retrieved 2007/10/02.