cis-Ethyl Cinnamate (contains up to 10% Ethyl dihydrocinnamate

Base Information

• Chemical Name: cis-Ethyl Cinnamate (contains up to 10% Ethyl dihydrocinnamate
• CAS No.: 4610-69-9
• Molecular Formula: C11H12O2
• Molecular Weight: 176.215
• Hs Code.: 2916399090
• Mol file: 4610-69-9.mol

Synonyms:cis-Ethyl Cinnamate;

Chemical Property of cis-Ethyl Cinnamate (contains up to 10% Ethyl dihydrocinnamate

Chemical Property:

• Boiling Point: 140 °C(Press: 18 Torr)
• PSA: 26.30000
• Density: 1.055±0.06 g/cm3(Predicted)
• LogP: 2.26290
• Storage Temp.: Refrigerator
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly)

Purity/Quality:

98%Min ^*data from raw suppliers

cis-EthylCinnamate(containsupto10%Ethyldihydrocinnamate) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: cis-Ethyl Cinnamate (contains up to 10% Ethyl dihydrocinnamate) (cas# 4610-69-9) is a compound useful in organic synthesis.

Technology Process of cis-Ethyl Cinnamate (contains up to 10% Ethyl dihydrocinnamate

There total 126 articles about cis-Ethyl Cinnamate (contains up to 10% Ethyl dihydrocinnamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

phenylpropynoic acid ethyl ester (2216-94-6) → (Z)-ethyl cinnamate (4610-69-9)

Guidance literature:

With α-(methylthio)benzyl methyl ether; hydrogen; palladium on activated charcoal; In ethyl acetate; for 48h;

DOI:10.1080/00304940009356749

Reference yield: 98.0%

phenylpropynoic acid ethyl ester (2216-94-6) → (Z)-ethyl cinnamate (4610-69-9) + ethyl dihydrocinnamate (2021-28-5)

Guidance literature:

With hydrogen; In methanol; at 40 ℃; for 6h; under 760.051 Torr;

DOI:10.1002/anie.201207845

Reference yield: 94.0%

benzaldehyde (100-52-7) + ethyl 2-[bis(2-isopropylphenoxy)phosphoryl]acetate (188945-44-0) → (Z)-ethyl cinnamate (4610-69-9)

Guidance literature:

ethyl 2-[bis(2-isopropylphenoxy)phosphoryl]acetate; With N-benzyl-trimethylammonium hydroxide; In tetrahydrofuran; methanol; at -78 ℃; for 0.25h; Inert atmosphere;

benzaldehyde; In tetrahydrofuran; methanol; for 10h; Inert atmosphere;

DOI:10.1016/j.phytochem.2012.08.001

upstream raw materials:

ethanol

ethyl 2-phenylpropanoate

diazoacetic acid ethyl ester

benzaldehyde

Downstream raw materials:

3,5c-diphenyl-4,5-dihydro-isoxazole-4r-carboxylic acid ethyl ester

(Z)-cinnamyl alcohol

ethyl (2S,3S)-3-phenyloxirane-2-carboxylate

ethyl (2R,3R)-3-phenyl-2,3-oxiranepropanoate

Refernces

• 1、 Go?owicz, Dariusz,Kazimierczuk, Krzysztof,Urbańczyk, Mateusz,Ratajczyk, Tomasz. "Monitoring Hydrogenation Reactions using Benchtop 2D NMR with Extraordinary Sensitivity and Spectral Resolution". . p. 196 - 200. Retrieved 2019.
• 2、 Janicki, Ignacy,Kie?basiński, Piotr. "A Straightforward, Purification-Free Procedure for the Synthesis of Ando and Still-Gennari Type Phosphonates". . p. 378 - 382. Retrieved 2021/10/21.
• 3、 Drikermann, Denis,Kupfer, Stephan,Seifert, Fabian,Steinmetzer, Johannes,Vilotijevic, Ivan,Zi, You. "Z-Selective phosphine promoted 1,4-reduction of ynoates and propynoic amides in the presence of water". supporting information. p. 6092 - 6097. Retrieved 2021/07/21.