Benzenepropanethioic acid, S-(pentafluorophenyl) ester

Base Information

• Chemical Name: Benzenepropanethioic acid, S-(pentafluorophenyl) ester
• CAS No.: 463298-63-7
• Molecular Formula: C15H9F5OS
• Molecular Weight: 332.294
• Mol file: 463298-63-7.mol

Synonyms:

Chemical Property of Benzenepropanethioic acid, S-(pentafluorophenyl) ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzenepropanethioic acid, S-(pentafluorophenyl) ester

There total 3 articles about Benzenepropanethioic acid, S-(pentafluorophenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

3-phenyl-propionaldehyde (104-53-0) + bis(pentafluorophenyl) disulfide (1494-06-0) → (S)-(2,3,4,5,6-pentafluorophenyl) 3-phenylpropanethioate (463298-63-7)

Guidance literature:

With cetyltrimethylammonim bromide; 2,2’-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride; In water; at 50 ℃; for 18h;

DOI:10.1039/b202129c DOI:10.1002/chem.200400754

Reference yield: 29.0%

3-phenyl-propionaldehyde (104-53-0) + pentafluorophenylthiol (771-62-0) → (S)-(2,3,4,5,6-pentafluorophenyl) 3-phenylpropanethioate (463298-63-7)

Guidance literature:

With cetyltrimethylammonim bromide; 2,2’-azobis[2-(2-imidazolin-2-yl)propane] dihydrochloride; In water; at 50 ℃; for 27h;

DOI:10.1002/chem.200400754

Reference yield: 17.0%

pentafluorophenylthiol (771-62-0) + 3-Phenylpropionic acid (501-52-0) → (S)-(2,3,4,5,6-pentafluorophenyl) 3-phenylpropanethioate (463298-63-7)

Guidance literature:

With dicyclohexyl-carbodiimide; In 1,4-dioxane; at 20 ℃; for 1.5h;

DOI:10.1016/j.jfluchem.2008.09.013

upstream raw materials:

3-phenyl-propionaldehyde

bis(pentafluorophenyl) disulfide

pentafluorophenylthiol

3-Phenylpropionic acid

Downstream raw materials:

3-phenylpropanoic acid methyl ester

N-hexyl-3-phenylpropionamide

dihydrochalcone

3-Phenylpropionic acid

Refernces

• 1、 Nambu, Hisanori,Hata, Kayoko,Matsugi, Masato,Kita, Yasuyuki. "Efficient synthesis of thioesters and amides from aldehydes by using an intermolecular radical reaction in water". . p. 719 - 727. Retrieved 2007/10/03.