Cyclohexane-1-carbaldehydeoxime

Base Information

• Chemical Name: Cyclohexane-1-carbaldehydeoxime
• CAS No.: 4715-11-1
• Molecular Formula: C7H13NO
• Molecular Weight: 127.186
• Mol file: 4715-11-1.mol

Synonyms:cyclohexanecarbaldoxime;cyclohexylaldoxime;cyclohexanecarbaldehyde oxime;cyclohexanecarboaldoxime;cyclohexanecarbaldehyde-oxime;cyclohexanecarboxaldoxime;

Chemical Property of Cyclohexane-1-carbaldehydeoxime

Chemical Property:

• PSA: 32.59000
• LogP: 2.02670

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexane-1-carbaldehydeoxime

There total 7 articles about Cyclohexane-1-carbaldehydeoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

cyclohexanecarbaldehyde (2043-61-0) → cyclohexanecarbaldoxime (4715-11-1)

Guidance literature:

With hydroxylamine hydrochloride;

DOI:10.1039/b305268k

Reference yield: 99.0%

→ cyclohexanecarbaldoxime (4715-11-1)

Guidance literature:

Reference yield: 8.0%

2-cyclohexyl-1,3-dioxolane (4362-48-5) → cyclohexanecarbaldoxime (4715-11-1) + cyclohexane carbonitrile (766-05-2)

Guidance literature:

With hydroxylamine hydrochloride; toluene-4-sulfonic acid; In ethanol; for 2h; Heating;

DOI:10.1248/cpb.41.2042

upstream raw materials:

cyclohexanecarbodithioic acid

2-cyclohexyl-1,3-dioxolane

Cyclohexyl iodide

cyclohexylmethyl alcohol

Downstream raw materials:

4-sec-butyl-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

2-cyclohexyl-5-oxo-4-(2-pivalamidoethyl)-2,5-dihydrooxazole 3-oxide

4-(2-carboxyethyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

4-(brmomethyl)-2-cyclohexyl-5-oxo-2,5-dihydrooxazole 3-oxide

Refernces

• 1、 Borini Etichetti, Carla M.,Cicetti, Soledad,Girardini, Javier E.,Sarotti, Ariel M.,Spanevello, Rolando A.,Suárez, Alejandra G.,Tsai, Yi-hsuan. "Design, synthesis and evaluation of novel levoglucosenone derivatives as promising anticancer agents". supporting information. . Retrieved 2020/06/03.
• 2、 Yang, Kai,Zhang, Feng,Fang, Tongchang,Zhang, Guan,Song, Qiuling. "Stereospecific 1,4-Metallate Shift Enables Stereoconvergent Synthesis of Ketoximes". supporting information. p. 13421 - 13426. Retrieved 2019/08/20.