[2-(Acetyloxy)-5-nitro-1,3-phenylene]di(methylene) diacetate

Base Information

• Chemical Name: [2-(Acetyloxy)-5-nitro-1,3-phenylene]di(methylene) diacetate
• CAS No.: 478951-91-6
• Molecular Formula: C14H15NO8
• Molecular Weight: 325.27100
• Mol file: 478951-91-6.mol

Synonyms:

Chemical Property of [2-(Acetyloxy)-5-nitro-1,3-phenylene]di(methylene) diacetate

Chemical Property:

• Melting Point: 74 - 75 °C (hexane)
• PSA: 124.72000
• LogP: 2.16950

Purity/Quality:

98%min ^*data from raw suppliers

[2-(Acetyloxy)-5-nitro-1,3-phenylene]di(methylene)diacetate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-(Acetyloxy)-5-nitro-1,3-phenylene]di(methylene) diacetate

There total 2 articles about [2-(Acetyloxy)-5-nitro-1,3-phenylene]di(methylene) diacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitro-phenol (100-02-7,78813-13-5,89830-32-0) → acetic acid 2,6-bis-acetoxymethyl-4-nitro-phenyl ester (478951-91-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / 18 h / 80 °C

2: 45.2 g / 23 h / 100 °C

In acetic acid;

DOI:10.1021/jo026152p

Reference yield:

acetic anhydride (108-24-7) + 2,6-bis(N-methylenemorpholino)-4-nitrophenol (153954-02-0) → acetic acid 2,6-bis-acetoxymethyl-4-nitro-phenyl ester (478951-91-6)

Guidance literature:

at 100 ℃; for 23h;

DOI:10.1021/jo026152p

Reference yield:

acetic acid 2,6-bis-acetoxymethyl-4-nitro-phenyl ester (478951-91-6) → 2,6-Bis-acetoxymethyl-4-nitro-phenol (108541-31-7)

Guidance literature:

With dmap; potassium carbonate; In methanol; N,N-dimethyl-formamide; at 20 ℃; for 4h;

DOI:10.1021/jo026152p

upstream raw materials:

acetic anhydride

2,6-bis(N-methylenemorpholino)-4-nitrophenol

4-nitro-phenol

Downstream raw materials:

2,6-Bis-acetoxymethyl-4-nitro-phenol

(3-hydroxymethyl-2-methoxymethoxy-5-nitro-phenyl)-methanol

Refernces