3,3-diphenylprop-2-en-1-ol

Base Information

• Chemical Name: 3,3-diphenylprop-2-en-1-ol
• CAS No.: 4801-14-3
• Molecular Formula: C15H14O
• Molecular Weight: 210.276
• DSSTox Substance ID: DTXSID00441414
• Nikkaji Number: J757.601C
• Mol file: 4801-14-3.mol

Synonyms:3,3-diphenyl-2-propene-1-ol;4801-14-3;3,3-diphenyl-prop-2-en-1-ol;3,3-diphenylprop-2-en-1-ol;diphenylvinylcarbinol;3,3-Diphenylallyl alcohol;SCHEMBL4630812;DTXSID00441414;VDZJHCQPPWSRFX-UHFFFAOYSA-N

Chemical Property of 3,3-diphenylprop-2-en-1-ol

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 210.104465066
• Heavy Atom Count: 16
• Complexity: 200

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=CCO)C2=CC=CC=C2

Technology Process of 3,3-diphenylprop-2-en-1-ol

There total 35 articles about 3,3-diphenylprop-2-en-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3,3-diphenyl-2-propenal (1210-39-5) → 3,3-diphenylprop-2-en-1-ol (4801-14-3)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 0 - 15 ℃; for 3h;

DOI:10.1002/anie.201403726

Reference yield: 100.0%

benzophenone (119-61-9) + vinyl magnesium bromide (1826-67-1) → 3,3-diphenylprop-2-en-1-ol (4801-14-3)

Guidance literature:

benzophenone; vinyl magnesium bromide; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Darkness;

With water; ammonium chloride; In tetrahydrofuran; Darkness;

DOI:10.1039/c8dt02168f

Reference yield: 98.0%

1,1-diphenylprop-2-en-1-ol (3923-51-1) → 3,3-diphenylprop-2-en-1-ol (4801-14-3)

Guidance literature:

With water; In 1,4-dioxane; at 100 ℃; for 12h;

DOI:10.1021/jo5004086

upstream raw materials:

ethyl 3,3-diphenylacrylate

methyl 3,3-diphenylacrylate

methanol

2-chloro-1,1-diphenylethene

Downstream raw materials:

3,3-diphenyl-2-propenal

1,1-diphenylpropane

3-bromo-1,1-diphenyl-1-propene

2.5-Dimethyl-3-(3.3-diphenyl-allyl)-benzochinon

Refernces

• 1、 Zhou, Xibing,Zhang, Guoying,Huang, Renbin,Huang, Hanmin. "Palladium-Catalyzed Allyl-Allyl Reductive Coupling of Allylamines or Allylic Alcohols with H2as Sole Reductant". supporting information. p. 365 - 369. Retrieved 2021/01/26.
• 2、 Da Camara, Bryce,Hooley, Richard J.,Ngai, Courtney,Woods, Connor Z.. "Size- And Shape-Selective Catalysis with a Functionalized Self-Assembled Cage Host". supporting information. p. 12862 - 12871. Retrieved 2021/09/28.