Edulan II

Base Information

• Chemical Name: Edulan II
• CAS No.: 41678-30-2
• Molecular Formula: C13H20O
• Molecular Weight: 192.3
• Mol file: 41678-30-2.mol

Synonyms:EDULAN II;(2S,8aS)-2,5,5,8a-Tetramethyl-3,5,6,8a-tetrahydro-2H-chromene;

Chemical Property of Edulan II

Chemical Property:

• PSA: 9.23000
• LogP: 3.46640

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Edulan II

There total 20 articles about Edulan II which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.0%

(2RS,4aSR,8aSR)-3,4,4a,5,6,8a-hexahydro-2,5,5,8a-tetramethyl-2H-1-benzopyran-4a-ol → edulan I (41678-29-9,41678-30-2,58116-28-2,58116-29-3,99881-86-4)

Guidance literature:

With pyridine; thionyl chloride; at 0 ℃; for 0.333333h;

Reference yield:

7,9,9-trimethyl-1,4-dioxa-spiro[4.5]dec-6-en-8-one (14203-64-6) → edulan I (41678-29-9,41678-30-2,58116-28-2,58116-29-3,99881-86-4)

Guidance literature:

Multi-step reaction with 6 steps

1: 1.) Mg, EtBr / 1.) THF, r.t., 1 h, 2.) THF, reflux, 15 h

2: 99 percent / H₂, KOH / Pd/Al₂O₃ / ethanol

3: 67 percent / 5percent HCl / acetone / 15 h

4: 30 percent / H₂ / PtO₂ / acetic acid

5: 80 percent / pyridine / tetrahydrofuran / 15 h

With pyridine; hydrogenchloride; potassium hydroxide; hydrogen; ethidium Bromide; magnesium; platinum(IV) oxide; palladium/alumina; In tetrahydrofuran; ethanol; acetic acid; acetone;

Reference yield:

(8RS,3'RS)-(Z)-8-(3-hydroxy-1-butenyl)-7,9,9-trimethyl-1,4-dioxaspiro<4.5>dec-6-en-8-ol → edulan I (41678-29-9,41678-30-2,58116-28-2,58116-29-3,99881-86-4)

Guidance literature:

Multi-step reaction with 4 steps

1: 67 percent / 5percent HCl / acetone / 15 h

2: 30 percent / H₂ / PtO₂ / acetic acid

3: 80 percent / pyridine / tetrahydrofuran / 15 h

With pyridine; hydrogenchloride; hydrogen; platinum(IV) oxide; In tetrahydrofuran; acetic acid; acetone;

upstream raw materials:

7,9,9-trimethyl-1,4-dioxa-spiro[4.5]dec-6-en-8-one

Refernces

• 1、 Weyerstahl, Peter,Meisel, Thomas. "Structure-Odor Correlation, XIX. Synthesis and Olfactory Properties of Various Racemic Theaspirones, Ketoedulans and Edulans". . p. 415 - 428. Retrieved 2007/10/02.