3-Amino-4-nitrobenzoic acid

Base Information

• Chemical Name: 3-Amino-4-nitrobenzoic acid
• CAS No.: 6968-22-5
• Molecular Formula: C7H6N2O4
• Molecular Weight: 182.136
• Hs Code.: 2922499990
• Mol file: 6968-22-5.mol

Synonyms:3-Amino-4-nitrobenzoicacid;NSC 20672;

Chemical Property of 3-Amino-4-nitrobenzoic acid

Chemical Property:

• Vapor Pressure: 7E-09mmHg at 25°C
• Refractive Index: 1.681
• Boiling Point: 449.9 °C at 760 mmHg
• Flash Point: 225.9 °C
• PSA: 109.14000
• Density: 1.568 g/cm³
• LogP: 1.97960
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99.90% ^*data from raw suppliers

3-Amino-4-nitrobenzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Amino-4-nitrobenzoic acid

There total 13 articles about 3-Amino-4-nitrobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-amino-4-nitrobenzoic acid methyl ester (99512-09-1) → 3-amino-4-nitrobenzoic acid (6968-22-5)

Guidance literature:

With sodium hydroxide; In methanol; at 20 ℃; for 1h;

DOI:10.1002/chem.201503548

Reference yield: 51.0%

4-nitro-benzoic acid (62-23-7) → 3-amino-4-nitrobenzoic acid (6968-22-5)

Guidance literature:

With O-Methylhydroxylamin; potassium tert-butylate; copper diacetate; In 1,2-dimethoxyethane; at 20 ℃; for 3h;

DOI:10.1039/a901537j

Reference yield:

N-(5-methyl-2-nitrophenyl)acetamide (7418-36-2) → 3-amino-4-nitrobenzoic acid (6968-22-5)

Guidance literature:

With potassium permanganate; Hydrolyse des Reaktionsprodukts mit wss. H₂SO₄;

upstream raw materials:

N-(5-methyl-2-nitrophenyl)acetamide

3-acetylamino-4-nitro-benzoic acid

ethyl 3-ethoxy-4-nitrobenzoate

4-nitro-3-(N'-nitro-ureido)-benzoic acid

Downstream raw materials:

3-hydroxy-4-nitro-benzoic acid

ammonia

3-amino-4-nitrobenzyl alcohol

2-nitro-5-ethoxycarbonylaniline

Refernces

• 1、 Winkler, Robert,Richter, Martin E. A.,Knuepfer, Uwe,Merten, Dirk,Hertweck, Christian. "Regio- and chemoselective enzymatic N-oxygenation in vivo, in vitro, and in flow". . p. 8016 - 8018. Retrieved 2007/10/03.