2-(BUT-1-YL)-TETRAHYDRO-4-H-1,3,6,2-DIOXAZABOROCINE

Base Information

• Chemical Name: 2-(BUT-1-YL)-TETRAHYDRO-4-H-1,3,6,2-DIOXAZABOROCINE
• CAS No.: 92527-13-4
• Molecular Formula: C₈H₁₈BNO₂
• Molecular Weight: 171.047
• Mol file: 92527-13-4.mol

Synonyms:1-Butaneboronicacid, cyclic ester with 2,2'-iminodiethanol (7CI); 1-Butaneboronic acid, iminodiethylene ester (6CI);2-Butyl-1,3,6,2-dioxazaborocane; NSC 404883

Chemical Property of 2-(BUT-1-YL)-TETRAHYDRO-4-H-1,3,6,2-DIOXAZABOROCINE

Chemical Property:

• Vapor Pressure: 0.0628mmHg at 25°C
• Boiling Point: 231.3°Cat760mmHg
• Flash Point: 93.7°C
• PSA: 30.49000
• Density: 0.92g/cm³
• LogP: 1.23990
• Storage Temp.: 2-8°C

Purity/Quality:

98% ^*data from raw suppliers

2-Butyl-1,3,6,2-dioxazaborocane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(BUT-1-YL)-TETRAHYDRO-4-H-1,3,6,2-DIOXAZABOROCINE

There total 2 articles about 2-(BUT-1-YL)-TETRAHYDRO-4-H-1,3,6,2-DIOXAZABOROCINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

butylboronic acid (4426-47-5) + 2,2'-iminobis[ethanol] (111-42-2) → [(2-)-N,O,O'[2,2'-iminobis[ethanolato]]]-2-butylboron (92527-13-4)

Guidance literature:

In diethyl ether; dichloromethane; (inert atm.);

DOI:10.1021/ja982055v

Reference yield:

butylboronic acid (4426-47-5) + 2,2'-iminobis[ethanol] (111-42-2) → 2-butyl-1,3,6,2-dioxazaborocane (92527-13-4)

Guidance literature:

DOI:10.1039/j39660001493

Reference yield: 93.0%

[(2-)-N,O,O'[2,2'-iminobis[ethanolato]]]-2-butylboron (92527-13-4) + (S,S)-(-)-2,3-dihydroxy-N,N,N',N'-tetramethylsuccinamide (63126-52-3) → (4S,5S)-2-butyl-N4,N4,N5,N5-tetramethyl-1,3,2-dioxaborolane-4,5-dicarboxamide (161344-84-9)

Guidance literature:

With sodium chloride; In dichloromethane; (inert atm.);

DOI:10.1021/ja982055v

upstream raw materials:

butylboronic acid

2,2'-iminobis[ethanol]

Downstream raw materials:

(4S,5S)-2-butyl-N⁴,N⁴,N⁵,N⁵-tetramethyl-1,3,2-dioxaborolane-4,5-dicarboxamide

Refernces

• 1、 -. "CYCLOPROPYL AMINE DERIVATIVES". Page/Page column 75; 79-80. . Retrieved 2008/06/13.
• 2、 Charette, André B.,Juteau, Hélène,Lebel, Hélène,Molinaro, Carmela. "Enantioselective cyclopropanation of allylic alcohols with dioxaborolane ligands: Scope and synthetic applications". . p. 11943 - 11952. Retrieved 2007/10/03.