Cholesteryl sodium sulfate

Base Information

• Chemical Name: Cholesteryl sodium sulfate
• CAS No.: 2864-50-8
• Molecular Formula: C27H45NaO4S
• Molecular Weight: 488.708
• Hs Code.: 2920909090
• Mol file: 2864-50-8.mol

Synonyms:Cholest-5-en-3-ol(3b)-, hydrogen sulfate, sodium salt(9CI);Cholesterol, hydrogen sulfate, sodium salt (8CI);Cholesteryl sodiumsulfate (6CI);Cholesterol 3-sulfate sodium salt;Cholesteryl sulfate sodiumsalt;Sodium cholesteryl sulfate;

Chemical Property of Cholesteryl sodium sulfate

Chemical Property:

• Appearance/Colour: White to off-white solid
• Melting Point: 178-180°C
• PSA: 74.81000
• LogP: 7.95400
• Storage Temp.: 2-8°C
• Solubility.: Methanol (Slightly, Heated)

Purity/Quality:

99%, ^*data from raw suppliers

Cholesterol3-SulfateSodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: Cholesterol sulfate is an endogenous component of cell membranes where it serves as a substrate for steroid synthesis, influences lipid metabolism, stabilizes cell membranes, regulates the activity of functional proteins, and plays a role in keratinocyte differentiation and development of the epidermal barrier. This synthetic formulation can be used to form nonconventional liposomes in order to study cellular membrane properties.
• Uses: Principal sterol of the higher animals. Found in all body tissues, especial in the brain, spinal cord, and in animal fats or oils. Main constituent of gallstones.

Technology Process of Cholesteryl sodium sulfate

There total 4 articles about Cholesteryl sodium sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

cholesterol 3-sulfate (1256-86-6,1491-95-8) → sodium (20R)-5-cholesten-3β-yl sulfate (2864-50-8)

Guidance literature:

With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 60 - 65 ℃; Reagent/catalyst; Temperature; Solvent;

Reference yield: 44.0%

cholesterol (57-88-5) → sodium (20R)-5-cholesten-3β-yl sulfate (2864-50-8)

Guidance literature:

cholesterol; With aminosulfonic acid; In N,N-dimethyl-formamide; at 63 ℃; for 2h;

With sodium hydrogencarbonate; In N,N-dimethyl-formamide;

Reference yield:

Pyridinium-cholesterylsulfat → sodium (20R)-5-cholesten-3β-yl sulfate (2864-50-8)

Guidance literature:

With sodium hydroxide; water;

DOI:10.1021/ja01850a030

upstream raw materials:

cholesterol mesylate

cholesterol

cholesterol 3-sulfate

Downstream raw materials:

cholesterol

cholesterol

Cholesteryl acetate

Refernces

• 1、 Gallo, Carmela,Nuzzo, Genoveffa,d'Ippolito, Giuliana,Manzo, Emiliano,Sardo, Angela,Fontana, Angelo. "Sterol Sulfates and Sulfotransferases in Marine Diatoms". . p. 101 - 138. Retrieved 2018.
• 2、 -. "Preparation method of medicinal sodium cholesteryl sulfate". Paragraph 0071-0075. . Retrieved 2020/05/14.