2-Propenoic acid, 3-(2-naphthalenyl)-, (2E)-

Base Information

• Chemical Name: 2-Propenoic acid, 3-(2-naphthalenyl)-, (2E)-
• CAS No.: 49711-14-0
• Molecular Formula: C13H10O2
• Molecular Weight: 198.221
• Mol file: 49711-14-0.mol

Synonyms:(E)-3-Naphthalen-2-yl-acrylic acid;(2E)-3-(naphth-1-yl)prop-2-enoic acid;3-(naphthalen-2-yl)acrylic acid;trans-3-(2'-Naphthyl)-propenoic acid;(E)-3-(naphthalene-2-yl)acrylic acid;(E)-3-(2-naphthyl)acrylic acid;(E)-3-(2-naphthyl)-2-propenoic acid;

Chemical Property of 2-Propenoic acid, 3-(2-naphthalenyl)-, (2E)-

Chemical Property:

• Melting Point: 203 - 204 °C
• Boiling Point: 393.1±11.0 °C(Predicted)
• PSA: 37.30000
• Density: 1.245±0.06 g/cm3(Predicted)
• LogP: 2.93760

Purity/Quality:

99% ^*data from raw suppliers

2-Naphthylacrylicacid >97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Propenoic acid, 3-(2-naphthalenyl)-, (2E)-

There total 16 articles about 2-Propenoic acid, 3-(2-naphthalenyl)-, (2E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

malonic acid (141-82-2) + β-naphthaldehyde (66-99-9) → (E)-3-(naphthalen-2-yl)acrylic acid (49711-14-0)

Guidance literature:

With piperidine; pyridine;

DOI:10.1016/j.ejmech.2017.02.006

Reference yield: 98.0%

ethyl (E)-3-(naphthalene-2-yl)acrylate (114833-06-6) → (E)-3-(naphthalen-2-yl)acrylic acid (49711-14-0)

Guidance literature:

In tetrahydrofuran; water;

Reference yield: 94.0%

diethylphosphonoacetic acid (3095-95-2) + β-naphthaldehyde (66-99-9) → (E)-3-(naphthalen-2-yl)acrylic acid (49711-14-0)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; zinc trifluoromethanesulfonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 25 ℃; for 12h;

DOI:10.1055/s-2006-950292

upstream raw materials:

malonic acid

β-naphthaldehyde

acetic anhydride

trans-3-(2-naphthyl)-propenoic acid butyl ester

Downstream raw materials:

N-phenyl 3-(2-naphthyl)acrylohydroxamic acid

C₄₄H₄₈O₁₂

13-[3-(2-naphthyl)propanoyl]-7,10-bis(2,2,2-trichloroethoxycarbonyl)baccatin III

(E)-N-[5-chloro-2-(5-oxo-4,5-dihydro-[1,2,4]oxadiazol-3-yl)-phenyl]-3-naphthalen-2-yl-acrylamide

Refernces

• 1、 Zhao, Bin,Xu, Bo. "Visible-light promoted oxidative cyclization of cinnamic acid derivatives using xanthone as the photocatalyst". supporting information. p. 568 - 573. Retrieved 2021/02/06.
• 2、 -. "Aryl amide derivatives and application thereof". Paragraph 0061-0063; 0077-0079. . Retrieved 2020/07/13.