17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Base Information

• Chemical Name: 17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid
• CAS No.: 128914-47-6
• Molecular Formula: C20H32 O3
• Molecular Weight: 320.4663
• DSSTox Substance ID: DTXSID201193624
• Nikkaji Number: J608.788D
• Wikidata: Q27132955
• Metabolomics Workbench ID: 2699
• Mol file: 128914-47-6.mol

Synonyms:17-HETE;128914-47-6;17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid;(5Z,8Z,11Z,14Z)-17-hydroxyicosa-5,8,11,14-tetraenoic Acid;(+/-)17-HETE;5,8,11,14-Eicosatetraenoic acid, 17-hydroxy-, (5Z,8Z,11Z,14Z)-;17-hydroxyeicosa-all-cis-5,8,11,14-tetraenoic acid;17-hydroxyeicosatetraenate;17-hydroxyarachidonic acid;17-hydroxy-arachidonic acid;CHEBI:63995;DTXSID201193624;(??)17-HETE;LMFA03060091;AKOS040754677;17-hydroxyeicosa-all-cis-5,8,11,14-tetraenoate;Q27132955;(all-cis)-17-hydroxy-5,8,11,14-eicosatetraenoic acid;(all-cis)-17-hydroxy-5,8,11,14-icosatetraenoic acid;(5Z,8Z,11Z,14Z)-17-Hydroxy-5,8,11,14-eicosatetraenoic acid;(5Z,8Z,11Z,14Z)-17-hydroxyeicosa-5,8,11,14-tetraenoic acid

Chemical Property of 17-hydroxy-5Z,8Z,11Z,14Z-eicosatetraenoic acid

Chemical Property:

• Vapor Pressure: 4.1E-11mmHg at 25°C
• Boiling Point: 477.3°C at 760 mmHg
• Flash Point: 256.6°C
• PSA: 57.53000
• Density: 0.984g/cm³
• LogP: 5.18750
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 14
• Exact Mass: 320.23514488
• Heavy Atom Count: 23
• Complexity: 392

Purity/Quality:

≥98% ^*data from raw suppliers

(±)17-HETE ≥98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(CC=CCC=CCC=CCC=CCCCC(=O)O)O
• Isomeric SMILES: CCCC(C/C=C\C/C=C\C/C=C\C/C=C\CCCC(=O)O)O
• Description: Electrolyte and fluid transport in the kidney are regulated in part by arachidonic acid and its metabolites. (±)17-HETE is the racemic version of a cytochrome P450 (CYP450) metabolite of arachidonic acid that has stereospecific effects on sodium transport in the kidney. At a concentration of 2 μM the (S)-enantiomer of 17-HETE inhibits proximal tubule ATPase activity by as much as 70%, whereas the (R)-isomer is inactive.