5-Diethylamino-2-nitrosophenol hydrochloride

Base Information

• Chemical Name: 5-Diethylamino-2-nitrosophenol hydrochloride
• CAS No.: 25953-06-4
• Molecular Formula: C10H14 N2 O2 . Cl H
• Molecular Weight: 230.694
• Hs Code.: 2922299090
• European Community (EC) Number: 631-080-0
• UNII: G89MM7DN9L
• DSSTox Substance ID: DTXSID4025036
• Mol file: 25953-06-4.mol

Synonyms:25953-06-4;5-(Diethylamino)-2-nitrosophenol hydrochloride;5-DIETHYLAMINO-2-NITROSOPHENOL HYDROCHLORIDE;2-NITROSO-5-DIETHYLAMINOPHENOL HYDROCHLORIDE;CCRIS 4614;5-(diethylamino)-2-nitrosophenol;hydrochloride;5-(Diethylamino)-2-nitrosophenol monohydrochloride;Phenol,5-(diethylamino)-2-nitroso-, monohydrochloride;5-(Diethylamino)-2-nitrosophenolhydrochloride;G89MM7DN9L;SCHEMBL103959;DTXSID4025036;AKOS016011168;LS-1090;CS-0235420;FT-0613221;N0259;EN300-156514;A818104;Phenol, 5-(diethylamino)-2-nitroso-, hydrochloride;2-NITROSO-5-DIETHYL AMINO PHENOL HYDROCHLORIDE;Phenol, 5-(diethylamino)-2-nitroso-, monohydrochloride;Phenol, 5-(diethylamino)-2-nitroso-, hydrochloride (1:1)

Chemical Property of 5-Diethylamino-2-nitrosophenol hydrochloride

Chemical Property:

• Vapor Pressure: 1.27E-05mmHg at 25°C
• Boiling Point: 358.1°Cat760mmHg
• Flash Point: 170.4°C
• PSA: 52.90000
• Density: g/cm³
• LogP: 3.43830
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 230.0822054
• Heavy Atom Count: 15
• Complexity: 183

Purity/Quality:

98%,99%, ^*data from raw suppliers

5-(Diethylamino)-2-nitrosophenolHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=CC(=C(C=C1)N=O)O.Cl

Technology Process of 5-Diethylamino-2-nitrosophenol hydrochloride

There total 4 articles about 5-Diethylamino-2-nitrosophenol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

3-diethylaminophenol (91-68-9) → 4-nitroso-3-hydroxy-N,N-diethylaniline hydrochloride (25953-06-4)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 0 ℃; for 2.5h; Inert atmosphere;

DOI:10.1039/c8ob01606b

Reference yield: 71.0%

3-diethylaminophenol (91-68-9) + isopentyl nitrite (110-46-3) → 4-nitroso-3-hydroxy-N,N-diethylaniline hydrochloride (25953-06-4)

Guidance literature:

In propan-1-ol;

Reference yield:

3-diethylaminophenol (91-68-9) → 5-diethylamino-2-nitrosophenol (6358-20-9) + 4-nitroso-3-hydroxy-N,N-diethylaniline hydrochloride (25953-06-4)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; at 0 - 5 ℃; for 4h;

DOI:10.1039/c2jm34946a

upstream raw materials:

3-diethylaminophenol

isopentyl nitrite

m-Hydroxyaniline

Downstream raw materials:

5-diethylamino-2-nitrosophenol

Nile Red

9-diethylamino-6-hydroxybenzo[a]phenoxazin-5-one

benzyl 6-(9-diethylamino-5-oxo-5H-benzo[a]phenoxazin-2-yloxy)hexanoate

Refernces

• 1、 Alves, Carla M.A.,Naik, Sarala,Coutinho, Paulo J.G.,Gon?alves, M. Sameiro T.. "New long alkyl side-chain benzo[a]phenoxazines as micellisation probes". . p. 4470 - 4474. Retrieved 2009.
• 2、 Liu, Keyin,Kong, Xiuqi,Ma, Yanyan,Lin, Weiying. "Rational Design of a Robust Fluorescent Probe for the Detection of Endogenous Carbon Monoxide in Living Zebrafish Embryos and Mouse Tissue". . p. 13489 - 13492. Retrieved 2017.
• 3、 Bautista-Gomez, Judith,Bossmann, Stefan H.,Higgins, Daniel A.,Hohn, Keith L.,Rafferty, Ryan J.,Usman, Abdulhafiz,Zhang, Man. "Fluorescence spectroscopy studies of crossed aldol reactions: A reactive Nile red dye reveals catalyst-dependent product formation". . p. 5579 - 5592. Retrieved 2020.
• 4、 Klán, Petr,Madea, Dominik,Martínek, Marek,Muchová, Lucie,Váňa, Ji?í,Vítek, Libor. "Structural modifications of nile red carbon monoxide fluorescent probe: Sensing mechanism and applications". . p. 3473 - 3489. Retrieved 2020/03/25.