5-Azachrysene

Base Information

• Chemical Name: 5-Azachrysene
• CAS No.: 218-38-2
• Molecular Formula: C17H11N
• Molecular Weight: 229.2759
• Mol file: 218-38-2.mol

Synonyms:benzophenanthridine;Benzo--phenanthridin;5-Azachrysene;Benzophenanthridin;

Chemical Property of 5-Azachrysene

Chemical Property:

• Vapor Pressure: 7.47E-08mmHg at 25°C
• Boiling Point: 449.7°Cat760mmHg
• Flash Point: 203.2°C
• PSA: 12.89000
• Density: 1.239g/cm³
• LogP: 4.54120

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Azachrysene

There total 61 articles about 5-Azachrysene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5-(methylsulfonyl)-5,6-dihydrobenzo[c]phenanthridine → benzo[c]phenanthridine (218-38-2)

Guidance literature:

With tetrabutyl ammonium fluoride; In acetonitrile; for 6h; Reflux;

DOI:10.1021/jo501910q

Reference yield: 90.0%

(4bR,10bS)-4b,10b-dihydrobenzo[c]phenanthridine → benzo[c]phenanthridine (218-38-2)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; at 80 ℃; for 4h; Inert atmosphere;

DOI:10.1021/acs.joc.1c01612

Reference yield: 90.0%

11,12-Dihydro-benzo[c]phenanthridine (98799-47-4) → benzo[c]phenanthridine (218-38-2)

Guidance literature:

palladium on activated charcoal; at 250 ℃; for 4h;

DOI:10.1021/jo00224a057

upstream raw materials:

5H-benzo[c]phenanthridin-6-one

N-(2-phenyl-[1]naphthyl)-formamide

7,8,9,10-tetrahydro-benzo[c]phenanthridine

6-chloro-benzo[c]phenanthridine

Refernces

• 1、 Badger,Seidler. "-". . p. 2329,2331. Retrieved 1954.
• 2、 Gadamer,Stichel. "-". . p. 491,499. Retrieved 1924.
• 3、 Aravindan, Narasingan,Jeganmohan, Masilamani. "A Short Total Synthesis of Benzophenanthridine Alkaloids via a Rhodium(III)-Catalyzed C-H Ring-Opening Reaction". . p. 14826 - 14843. Retrieved 2021/10/20.
• 4、 Saini, Gaurav,Kumar, Pravin,Kumar, Gangam Srikanth,Mangadan, Arun Raj Kizhakkayil,Kapur, Manmohan. "Palladium-Catalyzed α-Arylation of Silylenol Ethers in the Synthesis of Isoquinolines and Phenanthridines". supporting information. p. 441 - 444. Retrieved 2018/01/28.