Technology Process of Benzoic acid,
4-[[5-(acetylamino)-6-cyano-2,3-dihydro-1H-inden-1-yl]amino]-,
1,1-dimethylethyl ester
There total 4 articles about Benzoic acid,
4-[[5-(acetylamino)-6-cyano-2,3-dihydro-1H-inden-1-yl]amino]-,
1,1-dimethylethyl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
In
1-methyl-pyrrolidin-2-one;
at 140 ℃;
for 1.66667h;
DOI:10.1039/b301989f
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 43 percent / CrO3 / acetic acid / 55 °C
2: p-TsOH*H2O / 1,2-dimethoxy-ethane / 7 h / 110 °C
3: 0.520 g / sodium cyanoborohydride / methanol; acetic acid / 24 h / 20 °C
4: 70 percent / 1-methyl-pyrrolidin-2-one / 1.67 h / 140 °C
With
chromium(VI) oxide; sodium cyanoborohydride; toluene-4-sulfonic acid;
In
1-methyl-pyrrolidin-2-one; methanol; 1,2-dimethoxyethane; acetic acid;
4: Rosenmund-von Braun reaction;
DOI:10.1039/b301989f
- Guidance literature:
-
Multi-step reaction with 3 steps
1: p-TsOH*H2O / 1,2-dimethoxy-ethane / 7 h / 110 °C
2: 0.520 g / sodium cyanoborohydride / methanol; acetic acid / 24 h / 20 °C
3: 70 percent / 1-methyl-pyrrolidin-2-one / 1.67 h / 140 °C
With
sodium cyanoborohydride; toluene-4-sulfonic acid;
In
1-methyl-pyrrolidin-2-one; methanol; 1,2-dimethoxyethane; acetic acid;
3: Rosenmund-von Braun reaction;
DOI:10.1039/b301989f
