Benzene-o-diamine monohydrochloride

Base Information

• Chemical Name: Benzene-o-diamine monohydrochloride
• CAS No.: 615-28-1
• Molecular Formula: C6H8 N2 . 2 Cl H
• Molecular Weight: 181.065
• Hs Code.: 2921590090
• European Community (EC) Number: 254-318-1
• DSSTox Substance ID: DTXSID20192390
• Mol file: 615-28-1.mol

Synonyms:Benzene-o-diamine monohydrochloride;Benzene-o-diamine HCl;39145-59-0;EINECS 254-318-1;1,2-Benzenediamine, hydrochloride;SCHEMBL39680;o-phenylenediamine hydrochloride;o-Phenylenediamine, hydrochloride;DTXSID20192390;GNNALEGJVYVIIH-UHFFFAOYSA-N;o-phenylenediamine monohydrochloride;o-phenylenediamine monohydrochloride salt;FT-0606481

Chemical Property of Benzene-o-diamine monohydrochloride

Chemical Property:

• Vapor Pressure: 0.0149mmHg at 25°C
• Melting Point: 258 °C (dec.)(lit.)
• Boiling Point: 257°C at 760 mmHg
• Flash Point: 124.9°C
• PSA: 52.04000
• LogP: 3.61740
• Storage Temp.: 2-8°C
• Solubility.: H2O: 1 tablet/10 mL, clear, colorless
• Water Solubility.: Slightly soluble in water; freely soluble in alcohol, chloroform or ether
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 144.0454260
• Heavy Atom Count: 9
• Complexity: 62.9

Purity/Quality:

98%min ^*data from raw suppliers

1,2-Phenylenediamine Dihydrochloride [for Biochemical Research] >98.0%(HPLC)(N) ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,N,T
• Hazard Codes: Xn,N,T
• Statements: 22-40-43-51/53-68-50/53-36-25-20/21-36/37/38
• Safety Statements: 36/37-61-60-45-28-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N)N.Cl
• Uses: o-Phenylenediamine is a peroxidase substrate suitable for use in ELISA procedures. The substrate produces a soluble end product that is orange-brown in color and can be read spectrophotometrically at 450 nm. The OPD reaction may be stopped with 3 N HCl or 3 M H2SO4 and read at 492 nm. o-Phenylenediamine dihydrochloride has been used as a substrate for horseradish-peroxidase-conjugated secondary antibody in enzyme-linked immunosorbent assay (ELISA).

Technology Process of Benzene-o-diamine monohydrochloride

There total 2 articles about Benzene-o-diamine monohydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

1,2-Dinitrobenzene (528-29-0) → o-phenylenediamine dihydrochloride (615-28-1)

Guidance literature:

With hydrogenchloride; titanium(III) chloride; In water; for 2h; Reagent/catalyst; Kinetics; Activation energy; Electrochemical reaction;

DOI:10.1007/s11172-021-3298-9

Reference yield: 64.0%

2-nitro-aniline (88-74-4) → o-phenylenediamine dihydrochloride (615-28-1)

Guidance literature:

With hydrogenchloride; titanium(III) chloride; In water; for 2h; Electrochemical reaction;

DOI:10.1007/s11172-021-3298-9

Reference yield: 99.6%

2,2,2-Trifluoroacetophenone (434-45-7) + o-phenylenediamine dihydrochloride (615-28-1) → 2-phenyl-1H-benzoimidazole (716-79-0)

Guidance literature:

In N,N-dimethyl acetamide; at 120 - 130 ℃; for 24h;

DOI:10.1081/SCC-120015562

upstream raw materials:

1,2-Dinitrobenzene

2-nitro-aniline

Downstream raw materials:

alloxazine

N-picryl-m-phenylenediamine

N-(3-amino-phenyl)-succinamic acid

4-(2,4-diamino-phenylazo)-benzenesulfonic acid

Refernces