N-(2-Picolinoylphenyl)benzamide

Base Information

• Chemical Name: N-(2-Picolinoylphenyl)benzamide
• CAS No.: 91025-05-7
• Molecular Formula: C19H14 N2 O2
• Molecular Weight: 302.332
• Hs Code.: 2933399090
• European Community (EC) Number: 620-462-2
• NSC Number: 150843
• DSSTox Substance ID: DTXSID90302404
• Wikidata: Q82047169
• Mol file: 91025-05-7.mol

Synonyms:N-(2-Picolinoylphenyl)benzamide;91025-05-7;N-[2-(pyridine-2-carbonyl)phenyl]benzamide;NSC150843;Benzamide, N-[2-(2-pyridinylcarbonyl)phenyl]-;N-BENZOYL-2-(2-PYRIDINYLCARBONYL)-ANILINE;SCHEMBL9842617;AMY1847;DTXSID90302404;MFCD11110362;AKOS016006824;NSC 150843;NSC-150843;DS-18453;CS-0149862;C77101

Chemical Property of N-(2-Picolinoylphenyl)benzamide

Chemical Property:

• Vapor Pressure: 7.79E-08mmHg at 25°C
• Melting Point: 113-114 °C
• Boiling Point: 436.9°C at 760 mmHg
• PKA: 12.77±0.70(Predicted)
• Flash Point: 218°C
• PSA: 59.06000
• Density: 1.261g/cm³
• LogP: 3.63790
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 302.105527694
• Heavy Atom Count: 23
• Complexity: 418

Purity/Quality:

99% ^*data from raw suppliers

N-(2-Picolinoylphenyl)benzamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)NC2=CC=CC=C2C(=O)C3=CC=CC=N3

Technology Process of N-(2-Picolinoylphenyl)benzamide

There total 2 articles about N-(2-Picolinoylphenyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-phenyl-3-(2-pyridyl)indole (91025-04-6) → benzoic acid-[2-(pyridine-2-carbonyl)-anilide] (91025-05-7)

Guidance literature:

With ozone; ethyl acetate;

DOI:10.1039/jr9530003440

Reference yield:

1-phenyl-2-[2]pyridyl-ethanone-phenylhydrazone (91025-03-5) → benzoic acid-[2-(pyridine-2-carbonyl)-anilide] (91025-05-7)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated aqueous HCl

2: ozone; ethyl acetate

With hydrogenchloride; ozone; ethyl acetate;

DOI:10.1039/jr9530003440

Reference yield:

benzoic acid-[2-(pyridine-2-carbonyl)-anilide] (91025-05-7) → 2-(2-aminobenzoyl)pyridine (42471-56-7)

Guidance literature:

With hydrogenchloride;

DOI:10.1039/jr9530003440

upstream raw materials:

2-phenyl-3-(2-pyridyl)indole

1-phenyl-2-[2]pyridyl-ethanone-phenylhydrazone

Downstream raw materials:

2-(2-aminobenzoyl)pyridine