benzyl allylcarbaMate

Base Information

• Chemical Name: benzyl allylcarbaMate
• CAS No.: 5041-33-8
• Molecular Formula: C11H13NO2
• Molecular Weight: 191.23
• Hs Code.: 2924299090
• Mol file: 5041-33-8.mol

Synonyms:Benzyl N-allylcarbamate;(Phenylmethoxy)-N-prop-2-enylcarboxamide;N-(benzyloxycarbonylamino)acetaldehyde;H2C=CHCH2NHCbz;NH-Cbz-allylamine;Cbz-allylamine;allyl-carbamic acid benzyl ester;N-Cbz-allylamine;Benzyl allylcarbamate;N-Carbobenzyloxy-2-propenamine;

Chemical Property of benzyl allylcarbaMate

Chemical Property:

• PSA: 41.82000
• LogP: 2.30320

Purity/Quality:

97% ^*data from raw suppliers

BenzylAllylcarbamate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzyl allylcarbaMate

There total 15 articles about benzyl allylcarbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyl chloroformate (501-53-1,94274-21-2) + 1-amino-2-propene (107-11-9,30551-89-4) → N-(Benzyloxycarbonyl)allylamine (5041-33-8)

Guidance literature:

benzyl chloroformate; With sodium hydrogencarbonate; for 1h; Inert atmosphere;

1-amino-2-propene; In ethanol; water; at 0 - 20 ℃; for 13h; Inert atmosphere;

DOI:10.1021/ja303641p

Reference yield: 99.0%

3-fluoropropene (818-92-8) + benzyl chloroformate (501-53-1,94274-21-2) → N-(Benzyloxycarbonyl)allylamine (5041-33-8)

Guidance literature:

3-fluoropropene; In benzene-d6; at -20 ℃;

benzyl chloroformate; With sodium hydrogencarbonate; at -20 ℃; Further stages.;

DOI:10.1021/ja7106096

Reference yield: 96.0%

allyloxytrimethylsilane (18146-00-4) + benzyl chloroformate (501-53-1,94274-21-2) → N-(Benzyloxycarbonyl)allylamine (5041-33-8)

Guidance literature:

allyloxytrimethylsilane; With [(C₅H₅)2Zr(N-tert-butyldimethylsilyl)(THF)]; In benzene-d6; at 23 ℃; for 12h;

benzyl chloroformate; With potassium carbonate; In tetrahydrofuran; benzene-d6; at 23 ℃; for 12h;

DOI:10.1021/ja056132f

upstream raw materials:

allylisocyanate

benzyl alcohol

18-crown-6 ether

n-propylammonium N-n-propylcarbamate

Downstream raw materials:

(3-dihydroxyboranyl-propyl)-carbamic acid benzyl ester

5-<(benzyloxycarbonylamino)methyl>-3-bromo-2-isoxazoline

N-(benzyloxycarbonyl)propylamine

(R)-benzyl 2-methyl-3-oxopropylcarbamate

Refernces

• 1、 Abdellaoui, Hassane,Chen, Xingpeng,Xu, Jiaxi. "Efficient Synthesis of N-Benzyloxycarbonyl-2-aminoalkanesulfonyl Chlorides with Functionalized Side Chains". . p. 2250 - 2256. Retrieved 2017/05/05.
• 2、 -. "CONTRAST AGENTS". Page/Page column 30. . Retrieved 2017/11/10.