Card-20(22)-enolide,16-(acetyloxy)-3-[(2,6- dideoxy-3-O-methyl-â-D-lyxohexopyranosyl) oxy]-14-hydroxy-,(3â,5â,16â)-

Base Information

• Chemical Name: Card-20(22)-enolide,16-(acetyloxy)-3-[(2,6- dideoxy-3-O-methyl-â-D-lyxohexopyranosyl) oxy]-14-hydroxy-,(3â,5â,16â)-
• CAS No.: 508-22-5
• Molecular Formula: C₃₂H₄₈O₉
• Molecular Weight: 576.728
• Mol file: 508-22-5.mol

Synonyms:16β-Acetoxy-14-hydroxy-3β-(O3-methyl-β-D-lyxo-2,6-didesoxy-hexopyranosyloxy)-5β,14β-card-20(22)-enolid;16β-acetoxy-14-hydroxy-3β-(O3-methyl-β-D-lyxo-2,6-dideoxy-hexopyranosyloxy)-5β,14β-card-20(22)-enolide;nerigoside;Acetic acid (3S,5R,8R,9S,10S,13R,14S,16S,17R)-14-hydroxy-3-((2R,4R,5S,6R)-5-hydroxy-4-methoxy-6-methyl-tetrahydro-pyran-2-yloxy)-10,13-dimethyl-17-(5-oxo-2,5-dihydro-furan-3-yl)-hexadecahydro-cyclopenta[a]phenanthren-16-yl ester;

Chemical Property of Card-20(22)-enolide,16-(acetyloxy)-3-[(2,6- dideoxy-3-O-methyl-â-D-lyxohexopyranosyl) oxy]-14-hydroxy-,(3â,5â,16â)-

Chemical Property:

• Boiling Point: 693.7±55.0 °C(Predicted)
• PSA: 120.75000
• Density: 1.26±0.1 g/cm3(Predicted)
• LogP: 3.68100

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Card-20(22)-enolide,16-(acetyloxy)-3-[(2,6- dideoxy-3-O-methyl-â-D-lyxohexopyranosyl) oxy]-14-hydroxy-,(3â,5â,16â)-

There total 1 articles about Card-20(22)-enolide,16-(acetyloxy)-3-[(2,6- dideoxy-3-O-methyl-â-D-lyxohexopyranosyl) oxy]-14-hydroxy-,(3â,5â,16â)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3β-O-(β-D-sarmentosyl)-16β-acetoxy-14-hydroxy-5β,14β-card-20(22)-enolide (465-16-7,465-17-8,508-22-5,559-83-1,31087-94-2,144300-17-4,53177-88-1)

Guidance literature:

With enzyme-substance from seed of adenium multiflorum;

DOI:10.1002/hlca.19500330431

Reference yield: 25.0%

oleandrin (465-16-7,465-17-8,508-22-5,559-83-1,31087-94-2,144300-17-4,53177-88-1) → gitoxigenin (545-26-6)

Guidance literature:

With trifluoroacetic acid; In butan-1-ol; at 200 ℃; for 1.5h;

DOI:10.3390/molecules26103030

Reference yield:

oleandrin (465-16-7,465-17-8,508-22-5,559-83-1,31087-94-2,144300-17-4,53177-88-1) → oleandrigenin (465-15-6)

Guidance literature:

With hydrogenchloride; water; In ethanol; for 2h; Heating;

DOI:10.1007/BF01372612

Downstream raw materials:

oleandrigenin

4′-α-oleandrin

gitoxigenin