linderic acid

Base Information

• Chemical Name: linderic acid
• CAS No.: 505-92-0
• Molecular Formula: C₁₂H₂₂O₂
• Molecular Weight: 198.305
• Mol file: 505-92-0.mol

Synonyms:4-dodecenoic acid;

Chemical Property of linderic acid

Chemical Property:

• Melting Point: 0.7°C
• Refractive Index: 1.4529
• Boiling Point: 321.28°C (estimate)
• PSA: 37.30000
• Density: 0.9081
• LogP: 3.76790

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of linderic acid

There total 8 articles about linderic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(E)-ethyl dodec-4-enoate → (E)-dodec-4-enoic acid (55928-67-1,505-92-0)

Guidance literature:

With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/chem.201904028

Reference yield:

Octanal (124-13-0) → (E)-dodec-4-enoic acid (55928-67-1,505-92-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: tetrahydrofuran / 0 - 20 °C / Inert atmosphere

2.1: 1 h / 110 °C / Inert atmosphere

2.2: 12 h / Inert atmosphere; Heating

3.1: lithium hydroxide / tetrahydrofuran; water / 3 h / 20 °C / Inert atmosphere

With lithium hydroxide; In tetrahydrofuran; water;

DOI:10.1002/chem.201904028

Reference yield:

dec-1-en-3-ol (74824-56-9,74867-43-9,74867-44-0,51100-54-0) → (E)-dodec-4-enoic acid (55928-67-1,505-92-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 1 h / 110 °C / Inert atmosphere

1.2: 12 h / Inert atmosphere; Heating

2.1: lithium hydroxide / tetrahydrofuran; water / 3 h / 20 °C / Inert atmosphere

With lithium hydroxide; In tetrahydrofuran; water;

DOI:10.1002/chem.201904028

upstream raw materials:

β-Propiolactone

n-heptylmagnesium bromide

acetylene

n-hexyllithium

Downstream raw materials:

dodecen-(4c)-oic acid-⁽¹⁾-(4-bromo-phenacyl ester)

Refernces

• 1、 Fujisawa, Tamotsu,Umezu, Kazuto,Kawashima, Masatoshi. "NEW SYNTHETIC METHOD OF (Z)-4-ALKENOIC ACIDS USING RING-OPENING REACTION OF (Z)-4-HEXENOLIDE WITH ORGANOCOPPER REAGENT". . p. 1795 - 1798. Retrieved 2007/10/02.