Phenylbromoethyne

Base Information

• Chemical Name: Phenylbromoethyne
• CAS No.: 932-87-6
• Molecular Formula: C8H5Br
• Molecular Weight: 181.032
• Hs Code.: 2903999090
• Mol file: 932-87-6.mol

Synonyms:Benzene,(bromoethynyl)- (6CI,7CI,8CI,9CI);(Bromoethynyl)benzene;1-Bromo-2-phenylacetylene;1-Bromo-2-phenylethyne;1-Phenyl-2-bromoacetylene;2-Bromo-1-phenylacetylene;2-Bromo-1-phenylethyne;2-Bromoethynylbenzene;2-Phenylethynyl bromide;Bromo(phenyl)acetylene;Bromophenylethyne;Phenylacetylene bromide;Phenylbromoacetylene;Phenylethynyl bromide;b-Bromo-a-phenylacetylene;

Chemical Property of Phenylbromoethyne

Chemical Property:

• Vapor Pressure: 0.196mmHg at 25°C
• Refractive Index: 1.615
• Boiling Point: 217.4 °C at 760 mmHg
• Flash Point: 86 °C
• PSA: 0.00000
• Density: 1.51 g/cm³
• LogP: 2.39050
• Storage Temp.: ?20°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

(Bromoethynyl)benzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 20-41
• Safety Statements: 26-39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of Phenylbromoethyne

There total 48 articles about Phenylbromoethyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

aq. ammonium chloride + phenylacetylene (536-74-3) → N4 -(2,2-Dimethyl-1S-methylcarbamoyl-propyl)-2S,N1 -dihydroxy-3R-(5-phenyl-penta-2, 4-diiynyl)-succinamide + 1-Bromo-2-phenylacetylene (932-87-6)

Guidance literature:

With sodium hydroxide; bromine; In tetrahydrofuran;

Reference yield: 96.0%

potassium (2-phenylethynyl)trifluoroborate → 1-Bromo-2-phenylacetylene (932-87-6)

Guidance literature:

With tetra-N-butylammonium tribromide; In tetrahydrofuran; water; at 20 ℃; for 0.333333h; chemoselective reaction;

DOI:10.1021/ol9027144

Reference yield: 96.0%

2,2-dibromostyrene (7436-90-0) → 1-Bromo-2-phenylacetylene (932-87-6)

Guidance literature:

With potassium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; for 2h; cooling;

DOI:10.1016/S0040-4020(00)00920-0

upstream raw materials:

phenylethynylmagnesium bromide

bromocyane

benzenesulfonic anhydride

toluene-p-sulfonyl bromide

Downstream raw materials:

(±)-isopropyl(phenylethynyl)sulfane

diethyl phenylethynylphosphonate

(E)-1,4-Diphenylbut-1-en-3-yne

di (2-phenylethynyl) telluride

Refernces

• 1、 Eglinton,G.,McCrae,W.. "-". . p. 2295 - 2299. Retrieved 1963.
• 2、 Xu, Hailong,Chen, Rui,Ruan, Hongjie,Ye, Ruyi,Meng, Ling-Guo. "Visible-Light-Promoted Formation of C—C and C—P Bonds Derived from Evolution of Bromoalkynes under Additive-Free Conditions: Synthesis of 1,1-Dibromo-1-en-3-ynes and Alkynylphosphine Oxides". supporting information. p. 873 - 878. Retrieved 2021/03/04.
• 3、 Kumari, Arram Haritha,Kumar, Jangam Jagadesh,Krishna, Gamidi Rama,Reddy, Raju Jannapu. "Nickel-Catalyzed Difunctionalization of Alkynyl Bromides with Thiosulfonates and N -Arylthio Succinimides: A Convenient Synthesis of 1,2-Thiosulfonylethenes and 1,1-Dithioethenes". supporting information. p. 2850 - 2864. Retrieved 2021/05/18.