1-(4-Methoxyphenyl)acetoneoxime

Base Information

• Chemical Name: 1-(4-Methoxyphenyl)acetoneoxime
• CAS No.: 52271-41-7
• Molecular Formula: C10H13NO2
• Molecular Weight: 179.219
• Hs Code.: 2928000090
• Mol file: 52271-41-7.mol

Synonyms:2-Propanone,1-(4-methoxyphenyl)-,oxime;

Chemical Property of 1-(4-Methoxyphenyl)acetoneoxime

Chemical Property:

• PSA: 41.82000
• LogP: 2.08780

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-(4-Methoxyphenyl)acetoneoxime

There total 11 articles about 1-(4-Methoxyphenyl)acetoneoxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-methoxy-4-(2-nitro-1(Z)-propenyl)benzene (207511-16-8) → 4-methoxyphenylacetone oxime (52271-41-7)

Guidance literature:

With hydroxylamine hydrochloride; sodium acetate; In 1,4-dioxane; perchloric acid; dichloromethane; for 2h; Ambient temperature;

DOI:10.1246/cl.1983.607

Reference yield: 81.0%

4-methoxybenzyl methyl ketone (122-84-9) → 4-methoxyphenylacetone oxime (52271-41-7)

Guidance literature:

With hydroxylamine hydrochloride; sodium carbonate; In ethanol; water; for 24h; Heating;

Reference yield: 6.0%

4-(2-nitro-propenyl)-anisole (17354-63-1) → 4-methoxybenzyl methyl ketone (122-84-9) + 4-methoxyphenylacetone oxime (52271-41-7)

Guidance literature:

With sulfuric acid; toluene-4-sulfonic acid; In methanol; at 0 - 5 ℃; ceramic diaphragm, carbon-rod anode, platinum cathode, 4.5 F/mol, 0.1A, cathode potential -1.45 to -1.65V vs. SCE;

DOI:10.1021/jo00160a036

upstream raw materials:

4-(2-nitro-propenyl)-anisole

4-methoxybenzyl methyl ketone

1-methoxy-4-(2-nitro-1(Z)-propenyl)benzene

isopropyl alcohol

Downstream raw materials:

(E)-N-(1-(4-methoxyphenyl)prop-1-en-2-yl)acetamide

(Z)-N-(1-(4-methoxyphenyl)prop-1-en-2-yl)acetamide

(R)-N-[1-(4-methoxy-3-sulfamoylphenylpropan-2-yl)]acetamide

3β-(4-methylphenyl)-2β-[3'-(4-methoxybenzyl)isoxazol-5-yl]tropane

Refernces

• 1、 Lavernhe, Rémi,Torres-Ochoa, Rubén O.,Wang, Qian,Zhu, Jieping. "Copper-Catalyzed Aza-Sonogashira Cross-Coupling To Form Ynimines: Development and Application to the Synthesis of Heterocycles". supporting information. p. 24028 - 24033. Retrieved 2021/10/07.
• 2、 Yamamoto, Yutaro,Hasegawa, Hiroto,Yamataka, Hiroshi. "Dynamic path bifurcation in the Beckmann reaction: Support from kinetic analyses". experimental part. p. 4652 - 4660. Retrieved 2011/07/29.