2-CHLOROQUINOXALINE4-OXIDE

Base Information

• Chemical Name: 2-CHLOROQUINOXALINE4-OXIDE
• CAS No.: 5227-59-8
• Molecular Formula: C8H5ClN2O
• Molecular Weight: 180.593
• Hs Code.: 2933990090
• Mol file: 5227-59-8.mol

Synonyms:Quinoxaline,2-chloro-,4-oxide;3-Chloroquinoxaline 1-oxide;

Chemical Property of 2-CHLOROQUINOXALINE4-OXIDE

Chemical Property:

• PSA: 38.35000
• LogP: 2.31670

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-CHLOROQUINOXALINE4-OXIDE

There total 7 articles about 2-CHLOROQUINOXALINE4-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

2-chloroquinoxaline (1448-87-9) → 2-chloroquinoxaline-1-oxide (5227-57-6) + 3-chloroquinoxaline 1-oxide (5227-59-8) + 2-chloroquinoxaline N,N'-dioxide (50473-32-0)

Guidance literature:

With dipotassium peroxodisulfate; sulfuric acid; at 20 ℃; for 18h;

DOI:10.1016/j.tetlet.2010.07.148

Reference yield: 60.0%

2-chloroquinoxaline (1448-87-9) → 3-chloroquinoxaline 1-oxide (5227-59-8) + 2-chloroquinoxaline N,N'-dioxide (50473-32-0)

Guidance literature:

With HOF* CH₃CN; In chloroform; at 0 ℃;

DOI:10.1021/jo0608016

Reference yield: 6.0%

2-chloroquinoxaline (1448-87-9) → 3-chloroquinoxaline 1-oxide (5227-59-8)

Guidance literature:

With dihydrogen peroxide; acetic acid;

DOI:10.1016/j.molstruc.2020.128826

upstream raw materials:

peracetic acid

2-chloroquinoxaline

acetic acid

2,3-diethynylquinoxaline

Downstream raw materials:

3-chloro-2-quinoxalinecarbonitrile

quinoxaline-2,3-dicarbonitrile

4-benzoyl(cyano)methylene-4,5-dihydrotetrazolo<1,5-a>quinoxaline

2-chloroquinoxaline

Refernces

• 1、 Dahbi, Samir,Methnani, Ebtissem,Bisseret, Philippe. "First synthesis of 2-phosphonylated quinoxaline 1,4-dioxides: An extension to the Beirut reaction". scheme or table. p. 5516 - 5520. Retrieved 2010/10/21.
• 2、 -. "Tetrazolo(1,5-a)quinoxalines for control of phytopathogens". . . Retrieved 2008/06/13.