5,6-Dichlorovanillin

Base Information

• Chemical Name: 5,6-Dichlorovanillin
• CAS No.: 18268-69-4
• Molecular Formula: C8H6 Cl2 O3
• Molecular Weight: 221.04
• Hs Code.: 2913000090
• DSSTox Substance ID: DTXSID2075138
• Nikkaji Number: J451.256A
• Wikidata: Q82003169
• Mol file: 18268-69-4.mol

Synonyms:5,6-Dichlorovanillin;18268-69-4;2,3-DICHLORO-4-HYDROXY-5-METHOXYBENZALDEHYDE;Benzaldehyde, 2,3-dichloro-4-hydroxy-5-methoxy-;2,3-dichloro-4-hydroxy-5-methoxy-benzaldehyde;SCHEMBL7966625;DTXSID2075138;HY-133607;CS-0128384

Chemical Property of 5,6-Dichlorovanillin

Chemical Property:

• Vapor Pressure: 0.000261mmHg at 25°C
• Boiling Point: 313.9°Cat760mmHg
• Flash Point: 143.7°C
• PSA: 46.53000
• Density: 1.499g/cm³
• LogP: 2.52010
• XLogP3: 2.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 219.9693994
• Heavy Atom Count: 13
• Complexity: 188

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(=C(C(=C1)C=O)Cl)Cl)O

Technology Process of 5,6-Dichlorovanillin

There total 5 articles about 5,6-Dichlorovanillin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloroform (67-66-3,8013-54-5) + chlorine (7782-50-5) + vanillin (121-33-5,8014-42-4) → 5-chlorovanillin (19463-48-0) + 5,6-Dichlorovanillin (18268-69-4) + 2,5-Dichlorovanillin (140642-60-0)

Guidance literature:

DOI:10.1021/ja01374a061

Reference yield:

→ 5,6-Dichlorovanillin (18268-69-4)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/ja01374a061

Reference yield:

6-chlorovaniline (18268-76-3) → 5,6-Dichlorovanillin (18268-69-4)

Guidance literature:

With chloroform; chlorine;

DOI:10.1021/ja01374a061

upstream raw materials:

6-chlorovaniline

chloroform

chlorine

vanillin