2-(Tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid

Base Information Edit

Chemical Name:2-(Tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid
CAS No.:544479-61-0
Molecular Formula:C9H14F3NO4
Molecular Weight:257.21
Hs Code.:29225090
European Community (EC) Number:834-573-0
Mol file:544479-61-0.mol

Synonyms:544479-61-0;Boc-2-amino-4,4,4-trifluorobutyric acid;2-(tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid;2-{[(tert-butoxy)carbonyl]amino}-4,4,4-trifluorobutanoic acid;4,4,4-trifluoro-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid;MFCD08532484;(R,S)-Boc-2-amino-4,4,4-trifluoro-butyric acid;SCHEMBL355405;2-tert-butoxycarbonylamino-4,4,4-trifluoro-butyric acid;STR10037;MFCD02682446;AKOS013464751;AT27604;SY246468;2-(N-Boc-amino)-4,4,4-trifluorobutyric acid;EN300-151153;(S)-2-(Boc-amino)-4,4,4-trifluorobutanoic Acid;2-BOC-AMINO-4,4,4-TRIFLUOROBUTANOIC ACID;F8887-2773;Z1201004999;2-((tert-Butoxycarbonyl)amino)-4,4,4-trifluorobutanoicacid;2-((tert-Butoxycarbonyl)amino)-4,4,4-trifluorobutanoic acid;(R,S)-Boc-2-Amino-4,4,4-trifluoro-butyric acid (Boc-DL-Ala(CF3)-OH);2-({[(1,1-dimethylethyl)oxy]carbonyl}amino)-4,4,4-trifluorobutanoic acid

Suppliers and Price of 2-(Tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
Boc-2-amino-4,4,4-trifluorobutyric acid
100mg
$ 240.00

Matrix Scientific
Boc-2-amino-4,4,4-trifluorobutyric acid
1g
$ 923.00

Matrix Scientific
Boc-2-amino-4,4,4-trifluorobutyric acid
500mg
$ 600.00

Crysdot
2-((tert-Butoxycarbonyl)amino)-4,4,4-trifluorobutanoicacid 95+%
1g
$ 428.00

American Custom Chemicals Corporation
BOC-2-AMINO-4,4,4-TRIFLUOROBUTYRIC ACID 95.00%
500MG
$ 1658.58

American Custom Chemicals Corporation
BOC-2-AMINO-4,4,4-TRIFLUOROBUTYRIC ACID 95.00%
100MG
$ 490.00

AK Scientific
Boc-2-amino-4,4,4-trifluorobutyricacid
250mg
$ 225.00

Total 4 raw suppliers

Chemical Property of 2-(Tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid Edit

Chemical Property:

PSA：75.63000
LogP:2.30760
XLogP3:2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:257.08749241
Heavy Atom Count:17
Complexity:296

Purity/Quality:

98%min ^*data from raw suppliers

Boc-2-amino-4,4,4-trifluorobutyric acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC(F)(F)F)C(=O)O

Technology Process of 2-(Tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid

There total 1 articles about 2-(Tert-butoxycarbonylamino)-4,4,4-trifluorobutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.8%

: 15959-93-0
(DL)-2-amino-4,4,4-trifluorobutanoic acid

: 24424-99-5
di-tert-butyl dicarbonate

: 544479-61-0
2-[[(tert-butoxy)carbonyl]amino]-4,4,4-trifluorobutanoic acid

Guidance literature:: In dichloromethane; at 0 - 20 ℃; for 2h;

Reference yield: 89.0%

: 544479-61-0
2-[[(tert-butoxy)carbonyl]amino]-4,4,4-trifluorobutanoic acid

: 1403942-10-8
1-amino-N-phenyl-1H-pyrrole-2-carboxamide

: 1403943-06-5
tert-butyl 4,4,4-trifluoro-1-oxo-1-(2-(phenylcarbamoyl)-1H-pyrrol-1-ylamino)butan-2-ylcarbamate

Guidance literature:: 2-[[(tert-butoxy)carbonyl]amino]-4,4,4-trifluorobutanoic acid; With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 2h;

1-amino-N-phenyl-1H-pyrrole-2-carboxamide; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃;