Benzene, 1,3-bis(chloromethyl)-2,4,5,6-tetramethyl-

Base Information

• Chemical Name: Benzene, 1,3-bis(chloromethyl)-2,4,5,6-tetramethyl-
• CAS No.: 54490-78-7
• Molecular Formula: C12H16Cl2
• Molecular Weight: 231.165
• Mol file: 54490-78-7.mol

Synonyms:1,3-bis-chloromethyl-2,4,5,6-tetramethyl-benzene;1,2,3,5-Tetramethyl-4,6-bis-chlormethyl-benzol;4,6-Bis(chlormethyl)tetramethylbenzol;1,3-Bis-chlormethyl-2,4,5,6-tetramethyl-benzol;Benzene,1,3-bis(chloromethyl)-2,4,5,6-tetramethyl;2,4,5,6-tetramethyl-1,3-dichloromethylbenzene;

Chemical Property of Benzene, 1,3-bis(chloromethyl)-2,4,5,6-tetramethyl-

Chemical Property:

• PSA: 0.00000
• LogP: 4.39780

Purity/Quality:

99% ^*data from raw suppliers

ALPHA1,ALPHA3-DICHLOROHEXAMETHYLBENZENE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Total 1 MSDS from other Authors

Useful:

Technology Process of Benzene, 1,3-bis(chloromethyl)-2,4,5,6-tetramethyl-

There total 8 articles about Benzene, 1,3-bis(chloromethyl)-2,4,5,6-tetramethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.1%

1,2,3,5-Tetramethylbenzene (527-53-7) + chloromethyl methyl ether (107-30-2) → 2,4,5,6-tetramethyl-1,3-dichloromethylbenzene (54490-78-7)

Guidance literature:

With zinc(II) chloride; at 20 ℃; for 0.166667h;

DOI:10.3184/030823409X430185

Reference yield: 38.0%

C12H16FO3S(1+) → 2,4,5,6-tetramethyl-1,3-dichloromethylbenzene (54490-78-7)

Guidance literature:

With hydrogenchloride; lead dioxide; In fluorosulphonic acid; at -75 ℃; Product distribution;

Reference yield:

pentamethylbenzyl methyl ether (20145-50-0) → 2,3,4,5,6-pentamethylbenzyl alcohol (484-66-2) + 2,4,5,6-tetramethyl-1,3-dichloromethylbenzene (54490-78-7) + 2,4,6-tris(chloromethyl)-mesitylene (3849-01-2)

Guidance literature:

With hydrogenchloride; fluorosulphonic acid; lead dioxide; Yield given. Multistep reaction. Yields of byproduct given; 1. -75 grad C 2. - 40 grad C;

upstream raw materials:

1,2,3,5-Tetramethylbenzene

formaldehyd

Hexamethylbenzene

pentamethylbenzyl methyl ether

Downstream raw materials:

2,6-bis(sulfanylmethyl)-1,3,4,5-tetramethylbenzene

1,2,3,5-Tetramethyl-4,6-bis-<(2,2-bis-methansulfonyloxymethyl)-propyl>-benzol

1,2,3,5-Tetramethyl-4,6-bis-<(2,2-bis-hydroxymethyl)-propyl>-benzol

(3-Cyanomethyl-2,4,5,6-tetramethyl-phenyl)-acetonitrile

Refernces

• 1、 Shimizu, Tomoe,Hita, Katsuhiro,Paudel, Arjun,Tanaka, Junnji,Yamato, Takehiko. "Synthesis of polymethyl substituted [2.2]metaparacyclophanes and their Lewis-acid induced isomerisation to [2.2]metacyclophanes". experimental part. p. 244 - 247. Retrieved 2009/12/25.