Technology Process of 5,8,11-Trioxa-2-azadocosanoic acid, 22-mercapto-,
11-[ethoxy(4-nitrophenoxy)phosphinyl]undecyl ester
There total 8 articles about 5,8,11-Trioxa-2-azadocosanoic acid, 22-mercapto-,
11-[ethoxy(4-nitrophenoxy)phosphinyl]undecyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine; diothiothreitol;
In
methanol;
at 20 ℃;
for 20h;
Inert atmosphere;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: Fusarium solani pisi cutinase; water; propyl-phosphonic acid ethyl ester-(4-nitro-phenyl ester) / aq. phosphate buffer; dimethyl sulfoxide / 20 °C / pH 7 / Inert atmosphere; Enzymatic reaction
2.1: oxalyl dichloride / dichloromethane / 8 h / 0 - 20 °C / Inert atmosphere
2.2: 10 h / 20 °C / Inert atmosphere
3.1: triethylamine / N,N-dimethyl-formamide / 66 h / 60 °C / Inert atmosphere
4.1: triethylamine; diothiothreitol / methanol / 20 h / 20 °C / Inert atmosphere
With
oxalyl dichloride; propyl-phosphonic acid ethyl ester-(4-nitro-phenyl ester); water; triethylamine; diothiothreitol; Fusarium solani pisi cutinase;
In
methanol; aq. phosphate buffer; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: oxalyl dichloride / dichloromethane / 8 h / 0 - 20 °C / Inert atmosphere
1.2: 10 h / 20 °C / Inert atmosphere
2.1: triethylamine / N,N-dimethyl-formamide / 66 h / 60 °C / Inert atmosphere
3.1: triethylamine; diothiothreitol / methanol / 20 h / 20 °C / Inert atmosphere
With
oxalyl dichloride; triethylamine; diothiothreitol;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
![11-[2-(2-{2-[11-(pyridin-2-yldisulfanyl)undecyloxy]ethoxy}ethoxy)ethylcarbamoyloxy]undecylphosphonic acid ethyl ester 4-nitrophenyl ester](/Databaselist/images/loading.webp)
