1-Bromo-3-butylbenzene

Base Information

• Chemical Name: 1-Bromo-3-butylbenzene
• CAS No.: 54887-20-6
• Molecular Formula: C10H13Br
• Molecular Weight: 213.117
• Hs Code.: 2903999090
• Mol file: 54887-20-6.mol

Synonyms:1-bromo-3-butyl-benzene;Benzene,1-bromo-3-butyl;1-Brom-3-butyl-benzol;m-bromobutylbenzene;1-bromo-3-n-butylbenzene;3-Bromo-n-butylbenzene;

Chemical Property of 1-Bromo-3-butylbenzene

Chemical Property:

• PSA: 0.00000
• LogP: 3.79170
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98.5% ^*data from raw suppliers

3-Bromo-n-butylbenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Bromo-3-butylbenzene

There total 10 articles about 1-Bromo-3-butylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 39.0%

meta-bromobenzyl bromide (823-78-9) + propyl bromide (106-94-5) → 1-bromo-3-n-butylbenzene (54887-20-6)

Guidance literature:

propyl bromide; With magnesium; In tetrahydrofuran; for 1h; Heating;

meta-bromobenzyl bromide; In tetrahydrofuran; at -70 - -60 ℃; for 0.5h;

With dilithium tetrachlorocuprate; In tetrahydrofuran; for 2h;

DOI:10.1021/jm031115r

Reference yield:

C10H13BrN2 (519051-02-6) → 1-bromo-3-n-butylbenzene (54887-20-6)

Guidance literature:

With potassium hydroxide; In diethylene glycol dimethyl ether; at 150 ℃; for 6h;

Reference yield:

1-bromo-3-(but-3-en-1-yl)benzene (161173-98-4) → 1-bromo-3-n-butylbenzene (54887-20-6)

Guidance literature:

With 9-bora-bicyclo[3.3.1]nonane; In tetrahydrofuran; hexane; at 20 - 24 ℃;

upstream raw materials:

2-bromo-4-butylaniline

1-butylbenzene

ethanol

1-bromo-3-but-1-enyl-benzene

Downstream raw materials:

4-(3-bromophenyl)butan-1-ol

5-(3-butylphenyl)-1-phenyl-1H-pyrazol-3-ylamine

2-(3-butylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane

3-Butyl-benzoic acid 2-diethylamino-ethyl ester

Refernces

• 1、 -. "PYRAZOLE COMPOUND AND PHARMACEUTICAL USE THEREOF". Paragraph 0972; 973; 0974. . Retrieved 2013/04/13.
• 2、 Bolli, Martin H.,Marfurt, Judith,Grisostomi, Corinna,Boss, Christoph,Binkert, Christoph,Hess, Patrick,Treiber, Alexander,Thorin, Eric,Morrison, Keith,Buchmann, Stephan,Bur, Daniel,Ramuz, Henri,Clozel, Martine,Fischli, Walter,Weller, Thomas. "Novel benzo[1,4]diazepin-2-one derivatives as endothelin receptor antagonists". . p. 2776 - 2795. Retrieved 2007/10/03.