S-Phenyl diphenylphosphinothioate

Base Information

• Chemical Name: S-Phenyl diphenylphosphinothioate
• CAS No.: 5510-78-1
• Molecular Formula: C18H15OPS
• Molecular Weight: 310.356
• DSSTox Substance ID: DTXSID20546096
• Nikkaji Number: J1.154.451G
• Wikidata: Q82423800
• Mol file: 5510-78-1.mol

Synonyms:S-Phenyl diphenylphosphinothioate;5510-78-1;SCHEMBL10710925;DTXSID20546096

Chemical Property of S-Phenyl diphenylphosphinothioate

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 310.05812327
• Heavy Atom Count: 21
• Complexity: 330

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)SC3=CC=CC=C3

Technology Process of S-Phenyl diphenylphosphinothioate

There total 24 articles about S-Phenyl diphenylphosphinothioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N-phenylsulfonylpyrrole (16851-82-4) + Diphenylphosphine oxide (4559-70-0) → diphenylthiophosphinic acid-S-phenyl ester (5510-78-1) + diphenyl(1H-pyrrol-2-yl)phosphine oxide (62754-68-1)

Guidance literature:

With di-tert-butyl peroxide; In ethyl acetate; at 140 ℃; for 21h;

DOI:10.1002/adsc.201601204

Reference yield: 97.0%

1,1,2,2-tetraphenyldiphosphane-1,2-dioxide (1054-59-7) + diphenyldisulfane (882-33-7) → diphenylthiophosphinic acid-S-phenyl ester (5510-78-1)

Guidance literature:

With rhodium hydrido (PEt₃)3 complex; 1,2-bis-(diphenylphosphino)ethane; In tetrahydrofuran; for 0.5h; Heating;

DOI:10.1016/j.tetlet.2005.06.109

Reference yield: 96.0%

thiophenol (108-98-5) + Diphenylphosphine oxide (4559-70-0) → diphenylthiophosphinic acid-S-phenyl ester (5510-78-1)

Guidance literature:

With tert-Butyl peroxybenzoate; potassium iodide; In dimethyl sulfoxide; at 20 ℃; for 8h;

DOI:10.1039/c4gc00944d

upstream raw materials:

(phenylthio)acetic acid

Tetraphenyldiphosphin

thiophenol

Diphenylphosphinic chloride

Downstream raw materials:

phenylsulphur trifluoride

phenylsulfur(VI) trifluoridoxide

phenyltetrafluoro-λ⁶-sulfanyl chloride

diphenyl-phosphinic acid

Refernces

• 1、 Cheng, Feixiang,Liu, Jianjun,Liu, Teng,Yu, Rong,Zhang, Yanqiong. "An Alternative Metal-Free Aerobic Oxidative Cross-Dehydrogenative Coupling of Sulfonyl Hydrazides with Secondary Phosphine Oxides". . p. 253 - 262. Retrieved 2019/12/28.
• 2、 -. "Green synthetic method of thiohypophosphate". Paragraph 0010-0013. . Retrieved 2019/10/29.