2-Hydroxyphenyl phenyl sulfide

Base Information

• Chemical Name: 2-Hydroxyphenyl phenyl sulfide
• CAS No.: 55214-86-3
• Molecular Formula: C12H10OS
• Molecular Weight: 202.277
• Hs Code.: 2930909090
• DSSTox Substance ID: DTXSID70452577
• Nikkaji Number: J1.795.384B
• Wikidata: Q72481098
• Mol file: 55214-86-3.mol

Synonyms:2-phenylsulfanylphenol;2-HYDROXYPHENYL PHENYL SULFIDE;55214-86-3;2-(phenylthio)phenol;2-phenylsulfanyl-phenol;SCHEMBL487237;DTXSID70452577

Chemical Property of 2-Hydroxyphenyl phenyl sulfide

Chemical Property:

• Boiling Point: 320oC
• Flash Point: 156oC
• PSA: 45.53000
• Density: 1.25
• LogP: 3.54340
• XLogP3: 3.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 202.04523611
• Heavy Atom Count: 14
• Complexity: 166

Purity/Quality:

98% or more ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)SC2=CC=CC=C2O

Technology Process of 2-Hydroxyphenyl phenyl sulfide

There total 36 articles about 2-Hydroxyphenyl phenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

iodobenzene (591-50-4) + 2-Iodophenol (533-58-4) → 2-phenylsulfanyl-phenol (55214-86-3)

Guidance literature:

2-Iodophenol; With copper(ll) sulfate pentahydrate; ethane-1,2-dithiol; potassium hydroxide; In water; dimethyl sulfoxide; at 100 ℃; for 8h; Inert atmosphere;

iodobenzene; In water; dimethyl sulfoxide; N,N-dimethyl-formamide; at 120 ℃; for 18h; Inert atmosphere;

DOI:10.1002/adsc.201400941

Reference yield: 92.0%

2-phenylthiocyclohexanone (110452-14-7) → 2-phenylsulfanyl-phenol (55214-86-3)

Guidance literature:

With bromine; In chloroform; Ambient temperature;

DOI:10.1016/0040-4039(94)85328-2

Reference yield: 89.0%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + diphenyldisulfane (882-33-7) → 2-phenylsulfanyl-phenol (55214-86-3)

Guidance literature:

With iodine; toluene-4-sulfonic acid; dimethyl sulfoxide; at 80 ℃; for 12h; Reagent/catalyst; Sealed tube;

DOI:10.1002/adsc.201300493

upstream raw materials:

1-methoxy-2-(phenylthio)benzene

2-hydroxybromobenzene

thiophenol

diphenyldisulfane

Downstream raw materials:

2-benzenesulfinyl-phenol

2-(4-bromobutoxy)diphenyl sulfide

[Rh2(1,2-bis(diisopropylphosphino)ethane)2(μ-SC12H9)(μ-Cl)]

Refernces

• 1、 Khaef, Sepideh,Rostami, Abed,Khakyzadeh, Vahid,Zolfigol, Mohammad Ali,Taherpour, Avat Arman,Yarie, Meysam. "Regioselective Ortho‐C–H sulfenylation of free phenols catalyzed by Co(II)-immobilized on silica-coated magnetic nanoparticles". . . Retrieved 2020/01/22.
• 2、 -. "SULFONIUM COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS". Paragraph 0172-0173. . Retrieved 2018/04/20.