Tris(2,2,3,3-tetrafluoropropyl)phosphate

Base Information

• Chemical Name: Tris(2,2,3,3-tetrafluoropropyl)phosphate
• CAS No.: 563-10-0
• Molecular Formula: C9H9F12O4P
• Molecular Weight: 440.123
• Nikkaji Number: J2.541.471C
• Mol file: 563-10-0.mol

Synonyms:Tris(2,2,3,3-tetrafluoropropyl)phosphate;563-10-0;tris(2,2,3,3-tetrafluoropropyl) phosphate;SCHEMBL962591;YZQXAGZTJRSUJT-UHFFFAOYSA-N;MFCD00371442;E75011;Phosphoric acid tris(2,2,3,3-tetrafluoropropyl) ester

Chemical Property of Tris(2,2,3,3-tetrafluoropropyl)phosphate

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 12
• Exact Mass: 440.0046837
• Heavy Atom Count: 26
• Complexity: 419

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(C(C(F)F)(F)F)OP(=O)(OCC(C(F)F)(F)F)OCC(C(F)F)(F)F

Technology Process of Tris(2,2,3,3-tetrafluoropropyl)phosphate

There total 17 articles about Tris(2,2,3,3-tetrafluoropropyl)phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane (71879-02-2) + Hexafluoroacetone (684-16-2) → phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester) (563-10-0) + 2,2-bis(2,2,3,3-tetrafluoropropoxy)hexafluoropropane

Guidance literature:

at 150 ℃; for 6h; autoclave;

Reference yield: 74.0%

pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane (71879-02-2) + 4-bromo-benzaldehyde (1122-91-4) → phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester) (563-10-0) + 1-[Bis-(2,2,3,3-tetrafluoro-propoxy)-methyl]-4-bromo-benzene

Guidance literature:

at 200 ℃; for 8h; autoclave;

Reference yield: 72.0%

pentakis(2,2,3,3-tetrafluoropropoxy)phosphorane (71879-02-2) + p-Chlorothiophenol (106-54-7) → phosphoric acid tris-(2,2,3,3-tetrafluoro-propyl ester) (563-10-0) + 2,2,3,3-tetrafluoropropanol (76-37-9) + 1-Chloro-4-(2,2,3,3-tetrafluoro-propylsulfanyl)-benzene

Guidance literature:

at 150 ℃; for 4h;

upstream raw materials:

benzoyl cyanide

tris(2,2,3,3-tetrafluoropropyl)phosphite

bis(1,1,3-trihydroperfluoropropyl) hydrogen phosphate

2,2,3,3-tetrafluoropropanol

Refernces

• 1、 Krolevets, A. A.,Ragulin, L. I.. "REACTIONS OF DIBROMOTRICHLOROPHOSPHORANE WITH αH,αH,ωH-POLYFLUORO-1-ALKANOLS". . p. 818. Retrieved 2007/10/02.
• 2、 Fokin, A. V.,Studnev, Yu. N.,Rapkin, A. I.,Pasevina, K. I.,Kolomiets, A. F.. "OXIDATION OF BIS(α,α,ω-TRIHYDROPERFLUOROALKYL) AND TRIS(α,α,ω-TRIHYDROPERFLUOROALKYL) PHOSPHITES". . p. 1332 - 1334. Retrieved 2007/10/02.