Carbamothioic acid, (1,1-dimethylethyl)-, S-phenyl ester

Base Information

• Chemical Name: Carbamothioic acid, (1,1-dimethylethyl)-, S-phenyl ester
• CAS No.: 56741-04-9
• Molecular Formula: C11H15NOS
• Molecular Weight: 209.312
• Mol file: 56741-04-9.mol

Synonyms:

Chemical Property of Carbamothioic acid, (1,1-dimethylethyl)-, S-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbamothioic acid, (1,1-dimethylethyl)-, S-phenyl ester

There total 17 articles about Carbamothioic acid, (1,1-dimethylethyl)-, S-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

S-Phenyl benzenethiosulfonate (1212-08-4) + tert-butylisonitrile (119072-55-8,7188-38-7) → S-phenyl tert-butylcarbamothioate (56741-04-9) + (+/-)S-isopropyl phenylsulfinate (111698-34-1,114376-03-3,126188-13-4,52736-48-8)

Guidance literature:

With sodium iodide; In isopropyl alcohol; at 30 ℃; for 4h; Reagent/catalyst; Solvent; Time; Temperature;

DOI:10.1021/acs.orglett.6b01023

Reference yield: 87.0%

tert-butylisonitrile (119072-55-8,7188-38-7) + p-methoxyphenylsulfonothioic phenyl ester (1146-42-5) → S-phenyl tert-butylcarbamothioate (56741-04-9)

Guidance literature:

With sodium iodide; In isopropyl alcohol; at 90 ℃; for 16h;

DOI:10.1039/c9ob01040h

Reference yield: 85.0%

tert-butylisonitrile (119072-55-8,7188-38-7) + thiophenol (108-98-5) → S-phenyl tert-butylcarbamothioate (56741-04-9)

Guidance literature:

With water; iodine; In dimethyl sulfoxide; at 60 ℃; for 3h; Solvent; Temperature; Reagent/catalyst; Catalytic behavior; Mechanism; Schlenk technique;

DOI:10.1039/c8ob01855c

upstream raw materials:

phenyl chlorothioformate

tert-butylamine

phenyl thiocyanate

isobutene

Downstream raw materials:

diphenyldisulfane

N-tert-butyltrimethylacetamide

N-(tert-butyl)phenanthrene-9-carboxamide

N-t-butylbenzamide

Refernces

• 1、 Malviya, Bhanwar Kumar,Sharma, Siddharth,Verma, Ved Prakash. "Electrochemical metal- And oxidant-free synthesis of S-thiocarbamates". . p. 9491 - 9500. Retrieved 2021/11/17.
• 2、 Bao, Pengli,Wang, Leilei,Yue, Huilan,Shao, Yun,Wen, Jiangwei,Yang, Daoshan,Zhao, Xiaohui,Wang, Hua,Wei, Wei. "Metal-Free Catalytic Synthesis of Thiocarbamates Using Sodium Sulfinates as the Sulfur Source". . p. 2976 - 2983. Retrieved 2019/03/07.