3,4'-Dichloropropiophenone

Base Information Edit

Chemical Name:3,4'-Dichloropropiophenone
CAS No.:3946-29-0
Molecular Formula:C9H8 Cl2 O
Molecular Weight:203.068
Hs Code.:2914790090
European Community (EC) Number:223-537-4
NSC Number:36074
UNII:R2CZE36L2E
DSSTox Substance ID:DTXSID70192608
Nikkaji Number:J31.124C
Wikidata:Q72467772
Mol file:3946-29-0.mol

Synonyms:3,4'-Dichloropropiophenone;3946-29-0;3-chloro-1-(4-chlorophenyl)propan-1-one;C9H8Cl2O;1-Propanone, 3-chloro-1-(4-chlorophenyl)-;R2CZE36L2E;(2-CHLOROETHYL)-4-CHLOROPHENYLKETONE;3-chloro-4'-chloropropiophenone;2-(4-chlorobenzoyl)ethyl chloride;EINECS 223-537-4;MFCD00000992;NSC-36074;3-Chloro-1-(4-chlorophenyl)-1-propanone;3-Chloro-1-(4-chlorophenyl)propan-1-one;NSC36074;UNII-R2CZE36L2E;beta,4-Dichloropropiophenone;3,4\'-Dichloropropiophenone;4',beta-Dichloropropiophenone;SCHEMBL653535;DTXSID70192608;3,4'-Dichloropropiophenone, 95%;STR05428;NSC 36074;.BETA.,P-DICHLOROPROPIOPHENONE;P,.BETA.-DICHLOROPROPIOPHENONE;AKOS015888238;CS-W015474;PROPIOPHENONE, 3,4'-DICHLORO-;AC-23996;SY048486;.BETA.-CHLORO-P-CHLOROPROPIOPHENONE;2-CHLOROETHYL P-CHLOROPHENYL KETONE;P-CHLORO-.BETA.-CHLOROPROPIOPHENONE;2-CHLOROETHYL 4-CHLOROPHENYL KETONE;D2613;FT-0635069;3-Chloro-1-(4-chloro-phenyl)-propan-1-one;3-Chloro-1-(4-chlorophenyl)-1-propanone #;EN300-243966;A824557;3,4 inverted exclamation mark -Dichloropropiophenone;W-106428;4-(1,2-dimethylpyridin-1-ium-4-yl)-1,2-dimethyl-pyridin-1-ium dichloride

Suppliers and Price of 3,4'-Dichloropropiophenone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,4''-Dichloropropiophenone
50mg
$ 45.00

TCI Chemical
3,4'-Dichloropropiophenone >98.0%(GC)(T)
5g
$ 64.00

TCI Chemical
3,4'-Dichloropropiophenone >98.0%(GC)(T)
25g
$ 220.00

SynQuest Laboratories
3,4'-Dichloropropionphenone
25 g
$ 154.00

SynQuest Laboratories
3,4'-Dichloropropionphenone
100 g
$ 408.00

Sigma-Aldrich
3′,4′-Dichloropropiophenone 99%
5 g
$ 355.00

Matrix Scientific
3-Chloro-1-(4-chlorophenyl)propan-1-one 97%
5g
$ 51.00

Matrix Scientific
3-Chloro-1-(4-chlorophenyl)propan-1-one 97%
1g
$ 19.00

Matrix Scientific
3-Chloro-1-(4-chlorophenyl)propan-1-one 97%
10g
$ 80.00

Crysdot
3,4'-Dichloropropiophenone 97%
500g
$ 481.00

Total 42 raw suppliers

Chemical Property of 3,4'-Dichloropropiophenone Edit

Chemical Property:

Appearance/Colour:yellow to brown crystals or crystalline powder
Melting Point:47-53 ºC
Refractive Index:1.5500 (estimate)
Boiling Point:135-137 ºC (0.6 mmHg)，344.6 °C at 760 mmHg
Flash Point:81 ºC
PSA：17.07000
Density:1.262g/cm³
LogP:3.15160
Storage Temp.:Refrigerator
Solubility.:Chloroform (Sparingly), Methanol (Slightly)
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:3
Exact Mass:201.9952203
Heavy Atom Count:12
Complexity:151

Purity/Quality:

98%,99%, ^*data from raw suppliers

3,4''-Dichloropropiophenone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:C,Xi
Statements: 34-36/37-36/37/38
Safety Statements: 23-26-27-36/37/39-45-37/39

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)CCCl)Cl
Uses 3’,4’-Dichloropropiophenone is used as a reagent in the preparation of antidepressant aryl-alkyl-piperidine derivatives. Also used in the synthesis of mGlu5 receptor negative allosteric modulators. Also in the genetic screening of compounds countering the growth of methylthioadenosine phosphorylase involved in cancer spread.

Technology Process of 3,4'-Dichloropropiophenone

There total 3 articles about 3,4'-Dichloropropiophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%