Benzeneacetyl bromide, a-phenyl-

Base Information

• Chemical Name: Benzeneacetyl bromide, a-phenyl-
• CAS No.: 57369-76-3
• Molecular Formula: C14H11BrO
• Molecular Weight: 275.145
• Mol file: 57369-76-3.mol

Synonyms:

Chemical Property of Benzeneacetyl bromide, a-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetyl bromide, a-phenyl-

There total 2 articles about Benzeneacetyl bromide, a-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2,2-diphenylacetic acid (117-34-0) → diphenylacetyl bromide (57369-76-3)

Guidance literature:

With N-Bromosuccinimide; triphenylphosphine; In 1,4-dioxane; Heating;

Reference yield:

C20H26O2Si (105040-98-0) + dibromotriphenylphosphorane (1034-39-5) → diphenylacetyl bromide (57369-76-3)

Guidance literature:

In dichloromethane; Ambient temperature;

DOI:10.1021/jo00375a034

Reference yield: 96.0%

diphenylacetyl bromide (57369-76-3) + tert-butyl alcohol (75-65-0) → Diphenylessiggsaeure-tert-butylester (5350-81-2)

Guidance literature:

With aluminum oxide; In benzene; for 9h; Ambient temperature;

DOI:10.1246/cl.1994.209

upstream raw materials:

2,2-diphenylacetic acid

C₂₀H₂₆O₂Si

dibromotriphenylphosphorane

Downstream raw materials:

Diphenylessiggsaeure-tert-butylester

N-(3-bromopropyl)-2,2-diphenylacetamide

Refernces

• 1、 Pluempanupat, Wanchai,Chantarasriwong, Oraphin,Taboonpong, Piyada,Jang, Doo Ok,Chavasiri, Warinthorn. "Reactivity of chlorinating agents/PPh3 for the chlorination of alcohols and carboxylic acids: a comparative study". . p. 223 - 226. Retrieved 2007/10/03.
• 2、 Nagasawa, Kazuo,Ohhashi, Keiko,Yamashita, Asami,Ito, Keiichi. "Activated Basic Alumina Promotes a Mild, Clean and High-Yield Racemization-Free Synthesis of t-Butyl Esters from Chiral Acid Bromides and t-Butyl Alcohol". . p. 209 - 212. Retrieved 2007/10/02.