Sn-glycerol-1-phosphate

Base Information

• Chemical Name: Sn-glycerol-1-phosphate
• CAS No.: 5746-57-6
• Molecular Formula: C3H9O6P
• Molecular Weight: 172.075
• UNII: 196623779E
• DSSTox Substance ID: DTXSID501315267
• Nikkaji Number: J4.455E
• Wikipedia: Glycerol_1-phosphate
• Wikidata: Q19970447
• Metabolomics Workbench ID: 50423
• Mol file: 5746-57-6.mol

Synonyms:sn-glycerol-1-phosphate;L-Glycerol 1-phosphate;5746-57-6;L-alpha-glycerophosphate;Glyceryl 1-phosphate, (S)-;sn-Glycerol 1-phosphate;L-alpha-Glycerol phosphate;L-alpha-Glycerophosphoric acid;UNII-196623779E;[(2S)-2,3-dihydroxypropyl] dihydrogen phosphate;D-(glycerol 3-phosphate);L-(glycerol 1-phosphate);Glycerophosphoric acid L-alpha-form [MI];1,2,3-Propanetriol, 1-(dihydrogen phosphate), (2S)-;sn-glycerol 1-(dihydrogen phosphate);196623779E;sn-Gro-1-P;(2S)-2,3-dihydroxypropyl dihydrogen phosphate;3-phosphoglycerol;1GP;6tim;(S)-glyceryl 1-phosphate;D03MUW;SCHEMBL7341;CHEBI:16221;GLYCEROL 1-PHOSPHATE, L-;DTXSID501315267;L-.ALPHA.-GLYCEROPHOSPHATE;L-.ALPHA.-GLYCEROL PHOSPHATE;L-.ALPHA.-GLYCEROPHOSPHORIC ACID;3325-00-6;C00623;GLYCEROPHOSPHORIC ACID L-.ALPHA.-FORM [MI];Q19970447;sn-Glycerol 1-phosphate lithium salt, >=95.0% (TLC)

Chemical Property of Sn-glycerol-1-phosphate

Chemical Property:

• Boiling Point: 485.5±55.0 °C(Predicted)
• PKA: 1.84±0.10(Predicted)
• PSA: 117.03000
• Density: 1.738±0.06 g/cm3(Predicted)
• LogP: -1.55110
• XLogP3: -2.9
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 172.01367500
• Heavy Atom Count: 10
• Complexity: 129

Purity/Quality:

99% ^*data from raw suppliers

ALPHA-L-GLYCEROPHOSPHORIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(COP(=O)(O)O)O)O
• Isomeric SMILES: C([C@@H](COP(=O)(O)O)O)O
• Uses: [S,(+)]-1-O-Phosphono-L-glycerol is used to manufacture of certain glycerophosphates or to impart taste to solutions of glycerophosphates which are generally used medicinally. See also: Calcium Glycerophosphate.

Technology Process of Sn-glycerol-1-phosphate

There total 39 articles about Sn-glycerol-1-phosphate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.8%

glycerol (56-81-5,25618-55-7,64333-26-2,8013-25-0) → lysophosphatidic acid (57-03-4,1509-81-5,5746-57-6,17989-41-2)

Guidance literature:

With pyrophosphoric acid; trichlorophosphate; at 20 ℃; for 5h; Time;

Reference yield:

ethanol (64-17-5) + 1,2-di-O-stearoyl-rac-3-glycerophosphate (17966-25-5) → glycerol 2-phosphate, free acid (17181-54-3) + lysophosphatidic acid (57-03-4,1509-81-5,5746-57-6,17989-41-2) + stearic acid (57-11-4)

Guidance literature:

bei Raumtemperatur;

Reference yield:

hypophosphorous acid (6303-21-5) → lysophosphatidic acid (57-03-4,1509-81-5,5746-57-6,17989-41-2)

Guidance literature:

With aqueous ammonia; PPA; In glycerol;

upstream raw materials:

allyl dihydrophosphate

glycerol 2-phosphate, free acid

ethanol

1,2-di-O-stearoyl-rac-3-glycerophosphate

Downstream raw materials:

(+/-)-2,3-Di-O,O-caproyl-glycerin-1-phosphat

1,2-Dipalmitoylphosphatidic acid

dihydroxyacetone phosphate

formaldehyd

Refernces

• 1、 Koga, Yosuke,Ohga, Mami,Tsujimura, Masanari,Morii, Hiroyuki,Kawarabayasi, Yutaka. "Identification of sn-glycerol-1-phosphate dehydrogenase activity from genomic information on a hyperthermophilic archaeon, Sulfolobus tokodaii strain 7". . p. 282 - 285. Retrieved 2006.
• 2、 -. "Novel synthetic method to synthesize intermediate glycerophosphate from calcium glycerophosphate". Paragraph 0042; 0043; 0044; 0045. . Retrieved 2018/10/19.