2-(2-(2-Methoxyethoxy)ethoxy)ethyl methacrylate

Base Information

• Chemical Name: 2-(2-(2-Methoxyethoxy)ethoxy)ethyl methacrylate
• CAS No.: 24493-59-2
• Deprecated CAS: 133184-40-4
• Molecular Formula: C11H20 O5
• Molecular Weight: 232.277
• Hs Code.: 2916140000
• European Community (EC) Number: 246-288-3
• DSSTox Substance ID: DTXSID20885270
• Nikkaji Number: J109.547A
• Wikidata: Q82863885
• Mol file: 24493-59-2.mol

Synonyms:24493-59-2;2-(2-(2-Methoxyethoxy)ethoxy)ethyl methacrylate;METHYLTRIGLYCOLMETHACRYLATE;Triethylene glycol methyl ether methacrylate;2-[2-(2-methoxyethoxy)ethoxy]ethyl 2-methylprop-2-enoate;Methoxytriethyleneglycol methacrylate;2-[2-(2-methoxyethoxy)ethoxy]ethyl methacrylate;2-Propenoic acid, 2-methyl-, 2-[2-(2-methoxyethoxy)ethoxy]ethyl ester;EINECS 246-288-3;2-Propenoic acid, 2-methyl-, 2-(2-(2-methoxyethoxy)ethoxy)ethyl ester;SCHEMBL135538;DTXSID20885270;MFCD08275911;3,6,9-Trioxadecane-1-ol methacrylate;AS-80728;AM20090274;2-(2-(2-Methoxyethoxy)ethoxy)ethylmethacrylate;D82944;METHOXY TEG METHACRYLATE (STABILIZED WITH MEHQ);Triethylene glycol methyl ether methacrylate, contains MEHQ as inhibitor, 93%

Chemical Property of 2-(2-(2-Methoxyethoxy)ethoxy)ethyl methacrylate

Chemical Property:

• Vapor Pressure: 0.00158mmHg at 25°C
• Refractive Index: n20/D 1.446
• Boiling Point: 294.8 °C at 760 mmHg
• Flash Point: 124.4 °C
• PSA: 53.99000
• Density: 1.02 g/cm³
• LogP: 0.78530
• Storage Temp.: 2-8°C
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 11
• Exact Mass: 232.13107373
• Heavy Atom Count: 16
• Complexity: 203

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-[2-(2-Methoxyethoxy)ethoxy]ethyl methacrylate 94% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=C)C(=O)OCCOCCOCCOC

Technology Process of 2-(2-(2-Methoxyethoxy)ethoxy)ethyl methacrylate

There total 2 articles about 2-(2-(2-Methoxyethoxy)ethoxy)ethyl methacrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

triethylene glucol monomethyl ether (112-35-6,95507-80-5) + poly(methacrylic acid) (79-41-4,25087-26-7,50867-57-7) → 2-[2-(2-methoxyethoxy)ethoxy]ethyl methacrylate (24493-59-2)

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 25 ℃; for 48h; Inert atmosphere;

DOI:10.1021/acs.biomac.5b01545

Reference yield: 80.0%

triethylene glucol monomethyl ether (112-35-6,95507-80-5) + Methacryloyl chloride (920-46-7,26937-45-1) → 2-[2-(2-methoxyethoxy)ethoxy]ethyl methacrylate (24493-59-2)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; Inert atmosphere;

DOI:10.1039/c1cc15663b

upstream raw materials:

triethylene glucol monomethyl ether

Methacryloyl chloride

poly(methacrylic acid)

Refernces

• 1、 Yokoyama, Hideaki,Miyamae, Takayuki,Han, Seok,Ishizone, Takashi,Tanaka, Keiji,Takahara, Atsushi,Torikai, Naoya. "Spontaneously formed hydrophilic surfaces by segregation of block copolymers with water-soluble blocks". . p. 5180 - 5189. Retrieved 2005.
• 2、 Han, Seok,Hagiwara, Mamoru,Ishizone, Takashi. "Synthesis of thermally sensitive water-soluble polymethacrylates by living anionic polymerizations of oligo(ethylene glycol) methyl ether methacrylates". . p. 8312 - 8319. Retrieved 2003.
• 3、 Pramanik, Prithankar,Ray, Debes,Aswal, Vinod K.,Ghosh, Suhrit. "Supramolecularly Engineered Amphiphilic Macromolecules: Molecular Interaction Overrules Packing Parameters". supporting information. p. 3516 - 3520. Retrieved 2017/03/21.
• 4、 Mabuchi, Miyuki,Shimizu, Tadashi,Ueda, Masahiro,Mitamura, Kuniko,Ikegawa, Shigeo,Tanaka, Akito. "Improvement of solid material for affinity resins by application of long PEG spacers to capture the whole target complex of FK506". supporting information. p. 2788 - 2792. Retrieved 2015/06/08.