Technology Process of 6,7-dimethoxyindole
There total 2 articles about 6,7-dimethoxyindole which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: ammonium acetate; acetic acid / 1.5 h / 118 °C
2: silica gel; iron; acetic acid / 1 h / Reflux
With
ammonium acetate; silica gel; iron; acetic acid;
DOI:10.1016/j.ejmech.2010.12.012
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: KOH / dimethylformamide; ethanol
1.2: 73 percent / Ac2O; NaOAc / Heating
2.1: 85 percent / Fe / acetic acid; ethanol / 95 °C
With
potassium hydroxide; iron;
In
ethanol; acetic acid; N,N-dimethyl-formamide;
1.1: Henry reaction;
DOI:10.1016/S0040-4020(02)00243-0
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 94 percent / diethyl ether / 1 h / 0 °C
2: 96 percent / H2O / 3 h / 25 °C
3: 96 percent / LiAlH4 / tetrahydrofuran; diethyl ether / 4 h / Heating
4: 90 percent / NaOH / CTAB / CH2Cl2 / 12 h / 25 °C
5: 76 percent / acetonitrile / 0.5 h / 0 °C
6: 71 percent / BBr3 / CH2Cl2 / 12 h / 0 - 25 °C
With
sodium hydroxide; lithium aluminium tetrahydride; boron tribromide;
cetyltrimethylammonim bromide;
In
tetrahydrofuran; diethyl ether; dichloromethane; water; acetonitrile;
DOI:10.1016/S0040-4039(00)60427-6
