Cyclohexanamine, 4-chloro-

Base Information

• Chemical Name: Cyclohexanamine, 4-chloro-
• CAS No.: 59477-35-9
• Molecular Formula: C6H12ClN
• Molecular Weight: 133.621
• Mol file: 59477-35-9.mol

Synonyms:4-Chloro-cyclohexylamine;

Chemical Property of Cyclohexanamine, 4-chloro-

Chemical Property:

• Boiling Point: 82 - 87 °C (7 mmHg)
• PSA: 26.02000
• Density: 1.06±0.1 g/cm3(Predicted)
• LogP: 2.19540

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanamine, 4-chloro-

There total 5 articles about Cyclohexanamine, 4-chloro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

C6H10ClNO2 → 4-chlorocyclohexan-1-amine (59477-35-9)

Guidance literature:

With hydrogen; In ethanol; at 109.84 ℃; for 7.5h; under 18751.9 Torr; chemoselective reaction; Autoclave; Green chemistry;

DOI:10.1039/c5ra14382a

Reference yield:

4-chlorobenzonitrile (100-00-5) → 4-chlorocyclohexan-1-amine (59477-35-9) + 4-chloro-aniline (106-47-8)

Guidance literature:

With hydrogen; In water; at 50 ℃; for 6h; under 3750.38 Torr; Autoclave;

DOI:10.1016/j.apcata.2020.117536

Reference yield:

4-chloro-aniline (106-47-8) + carbonic acid dimethyl ester (616-38-6) → 4-chlorocyclohexan-1-amine (59477-35-9) + C8H14ClNO2

Guidance literature:

With hydrogen; sodium carbonate; at 160 ℃; for 2h; under 62256.2 Torr; Autoclave;

DOI:10.1016/j.apcata.2014.09.013

upstream raw materials:

4-chlorobenzonitrile

4-chloro-aniline

carbonic acid dimethyl ester

[1,3]-dioxolan-2-one

Refernces

• 1、 Ren, Ren,Ma, Jiantai. "Lamellar Ni/Al-SBA-15 fibers: Preparation, characterization, and applications as highly efficient catalysts for amine and imine syntheses". . p. 74802 - 74810. Retrieved 2015/09/21.