Benzene, (1-methoxypropyl)-

Base Information

• Chemical Name: Benzene, (1-methoxypropyl)-
• CAS No.: 59588-12-4
• Molecular Formula: C10H14O
• Molecular Weight: 150.221
• Mol file: 59588-12-4.mol

Synonyms:Methyl-(1-phenyl-propyl)-aether;1-phenyl-1-methoxypropane;(1-methoxypropyl)benzene;methyl-(1-phenyl-propyl)-ether;Benzene,(1-methoxypropyl);

Chemical Property of Benzene, (1-methoxypropyl)-

Chemical Property:

• PSA: 9.23000
• LogP: 2.78410

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Benzene, (1-methoxypropyl)-

There total 32 articles about Benzene, (1-methoxypropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.2%

1-Phenyl-1-propanol (93-54-9) + methyl iodide (74-88-4) → (1-methoxypropyl)benzene (59588-12-4)

Guidance literature:

1-Phenyl-1-propanol; With sodium hydride; In tetrahydrofuran; at 20 ℃; for 1h;

methyl iodide; at 20 ℃;

DOI:10.1002/chem.201701404

Reference yield: 98.0%

C30H40AuOP → (1-methoxypropyl)benzene (59588-12-4)

Guidance literature:

With chloro-trimethyl-silane; In dichloromethane-d2; at -78 ℃; for 0.0166667h; Reagent/catalyst; Inert atmosphere;

DOI:10.1021/acs.organomet.0c00324

Reference yield: 76.0%

C30H40AuOP → cyclopropylbenzene (873-49-4) + (1-methoxypropyl)benzene (59588-12-4)

Guidance literature:

With diethylaluminium chloride; In dichloromethane-d2; at -35 ℃; for 1h; Inert atmosphere;

DOI:10.1021/acs.organomet.0c00324

upstream raw materials:

1-phenyl-propan-1-one

methyl p-toluene sulfonate

methanol

3-phenyl-2-propanol

Downstream raw materials:

methyl 2-methyl-3-phenylpropionate

methyl 3-(benzyl)propanoate

methyl 2-phenylbutanoate

2-bromo-1-phenyl-1-propanone

Refernces

• 1、 Ayub, Rabia,Papadakis, Raffaello,Jorner, Kjell,Zietz, Burkhard,Ottosson, Henrik. "Cyclopropyl Group: An Excited-State Aromaticity Indicator?". supporting information. p. 13684 - 13695. Retrieved 2017/09/07.
• 2、 Ito, Shingo,Fujiwara, Yu-Ichi,Nakamura, Eiichi,Nakamura, Masaharu. "Iron-catalyzed cross-coupling of alkyl sulfonates with arylzinc reagents". supporting information; experimental part. p. 4306 - 4309. Retrieved 2009/12/26.