Phenylsuccinic anhydride

Base Information

• Chemical Name: Phenylsuccinic anhydride
• CAS No.: 1131-15-3
• Molecular Formula: C₁₀H₈O₃
• Molecular Weight: 176.172
• Hs Code.: 29173995
• Mol file: 1131-15-3.mol

Synonyms:2-Phenylsuccinic anhydride;

Chemical Property of Phenylsuccinic anhydride

Chemical Property:

• Vapor Pressure: 3.23E-05mmHg at 25°C
• Melting Point: 53-55 °C(lit.)
• Refractive Index: 1.567
• Boiling Point: 355 °C at 760 mmHg
• Flash Point: 175.1 °C
• PSA: 43.37000
• Density: 1.286 g/cm³
• LogP: 1.24370
• Solubility.: soluble in Methanol

Purity/Quality:

98%,99%, ^*data from raw suppliers

Phenylsuccinic Anhydride ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Phenylsuccinic Anhydride is a reagent used in the synthesis of hydroxypropyl methylcellulose esters.

Technology Process of Phenylsuccinic anhydride

There total 20 articles about Phenylsuccinic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2-phenylsuccinic acid (635-51-8,10424-29-0) → 2-phenylsuccinic anhydride (1131-15-3,112489-85-7)

Guidance literature:

With trimethylsilylethoxyacetylene; In dichloromethane; at 40 ℃; for 5h;

DOI:10.1021/jo00372a010

Reference yield: 93.0%

→ 2-phenylsuccinic anhydride (1131-15-3,112489-85-7)

Guidance literature:

With [(tetra(4-chlorophenyl)porphyrinato)aluminium(III)bis(tetrahydrofuran)][tetracarbonylcobaltate]; In 1,4-dioxane; at 90 ℃; for 3h; under 43958.7 Torr;

Reference yield: 27.0%

carbon dioxide (124-38-9,18923-20-1) + phenylacetylene (536-74-3) → tetrahydro-2,5-dioxo-4-phenylfuran-3-carboxylic acid (1314078-22-2) + 2-phenylsuccinic anhydride (1131-15-3,112489-85-7)

Guidance literature:

carbon dioxide; phenylacetylene; With aluminium hydride; copper(l) iodide; tetrabutylammomium bromide; nickel; In N,N-dimethyl-formamide; at 20 ℃; under 30003 Torr; Electrochemical reaction;

With hydrogenchloride; water; In N,N-dimethyl-formamide; for 3h;

DOI:10.1002/cjoc.201090285

upstream raw materials:

2-phenylsuccinic acid

maleic anhydride

benzene

1-(2'-methylpropenylidene)-2-phenylcyclopropane

Downstream raw materials:

4-oxo-2-phenyl-4-(o-tolyl)butanoic acid

2-phenylmaleic anhydride

4-(3,4-dimethoxy-phenyl)-4-oxo-2-phenyl-butyric acid

4-biphenyl-4-yl-4-oxo-3-phenyl-butyric acid

Refernces

• 1、 -. "Succinic anhydrides from epoxides". Page/Page column 24; 25; 26; 29; 30. . Retrieved 2013/07/25.
• 2、 Li, Chuanhua,Yuan, Gaoqing,Jiang, Huanfeng. "Electrocarboxylation of alkynes with carbon dioxide in the presence of metal salt catalysts". experimental part. p. 1685 - 1689. Retrieved 2011/07/07.