2,2-Dimethyl-1,3-dithiane

Base Information

• Chemical Name: 2,2-Dimethyl-1,3-dithiane
• CAS No.: 6007-22-3
• Molecular Formula: C6H12S2
• Molecular Weight: 148.293
• Hs Code.: 2934999090
• Mol file: 6007-22-3.mol

Synonyms:1,3-Dithiane,2,2-dimethyl;2,2-Dimethyl-[1,3]dithian;2,2-dimethyl-[1,3]dithiane;m-Dithiane,2,2-dimethyl;

Chemical Property of 2,2-Dimethyl-1,3-dithiane

Chemical Property:

• PSA: 50.60000
• LogP: 2.59260

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-Dimethyl-1,3-dithiane

There total 7 articles about 2,2-Dimethyl-1,3-dithiane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1.3-propanedithiol (109-80-8) + acetone (67-64-1) → 2,2-dimethyl-1,3-dithiane (6007-22-3)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 25 ℃;

DOI:10.1021/jo800938d

Reference yield: 90.8%

ethane-1,2-dithiol (540-63-6) + acetone (67-64-1) → 2,2-dimethyl-1,3-dithiane (6007-22-3)

Guidance literature:

With toluene-4-sulfonic acid; In toluene; for 24h; Inert atmosphere; Reflux;

Reference yield: 86.0%

1.3-propanedithiol (109-80-8) + 2,2-dimethoxy-propane (77-76-9) → 2,2-dimethyl-1,3-dithiane (6007-22-3)

Guidance literature:

With Kaolinitic clay; In tetrachloromethane; for 4h; Heating;

DOI:10.1039/a706475f

upstream raw materials:

1.3-propanedithiol

acetone

2-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]acetaldehyde

2,2-dimethoxy-propane

Downstream raw materials:

1,2-dithiolane 1-oxide

acetone

(-)-(1S)-2,2-dimethyl-1,3-dithian 1-oxide

(R)-2,2-dimethyl-1,3-dithiane-1-oxide

Refernces

• 1、 Fuchs, Christian,Edgar, Mark,Elsegood, Mark R. J.,Weaver, George W.. "Studies on the double alkylation of 2,2-disubstituted-1,3- dithiacycloalkane-S-oxides: Synthesis of tertiary thiol derivatives". . p. 21911 - 21918. Retrieved 2013/11/06.
• 2、 -. "ACE-INHIBITORS HAVING ANTIOXIDANT AND NO-DONOR ACTIVITY". Page/Page column 51. . Retrieved 2010/02/07.