3-methoxy-2-(methoxycarbonyl)benzoic acid

Base Information

• Chemical Name: 3-methoxy-2-(methoxycarbonyl)benzoic acid
• CAS No.: 60314-08-1
• Molecular Formula: C10H10O5
• Molecular Weight: 210.186
• Mol file: 60314-08-1.mol

Synonyms:2-methyl 3-methoxyphthalate;3-methoxy-phthalic acid-2-methyl ester;1,2-Benzenedicarboxylic acid,3-methoxy-,2-methyl ester;3-Methoxy-2-methoxycarbonyl-benzoesaeure;2-Carbomethoxy-3-methoxy-benzoesaeure;2-carbomethoxy-3-methoxybenzoic acid;3-Methoxy-phthalsaeure-2-methylester;

Chemical Property of 3-methoxy-2-(methoxycarbonyl)benzoic acid

Chemical Property:

• Vapor Pressure: 3E-06mmHg at 25°C
• Boiling Point: 373.7oC at 760 mmHg
• Flash Point: 149.4oC
• PSA: 75.66000
• Density: 1.282g/cm3
• LogP: -0.15470

Purity/Quality:

99% ^*data from raw suppliers

3-methoxy-2-(methoxycarbonyl)benzoicacid 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methoxy-2-(methoxycarbonyl)benzoic acid

There total 4 articles about 3-methoxy-2-(methoxycarbonyl)benzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dimethyl 3-methoxyphthalate (32136-52-0) → 2-methyl 3-methoxyphthalate (60314-08-1)

Guidance literature:

With potassium hydrogencarbonate; In methanol; water; for 24h; Product distribution; Heating; other reagents and solvents at various temperatures;

Reference yield:

→ 2-methyl 3-methoxyphthalate (60314-08-1) + 4-methoxybenzoic acid (100-09-4)

Guidance literature:

With chloroform; ozone; anschliessendes Erhitzen mit Wasser;

Reference yield:

dimethyl 3-nitrophthalate (13365-26-9) → 2-methyl 3-methoxyphthalate (60314-08-1)

Guidance literature:

With sodium methylate; In N,N,N,N,N,N-hexamethylphosphoric triamide;

upstream raw materials:

dimethyl 3-methoxyphthalate

dimethyl 3-nitrophthalate

Downstream raw materials:

2-<2,5-dimethoxybenzyl>-3-methoxybenzoic acid

3-(2,5-dimethoxyphenyl)-3-hydroxy-4-methoxy-1(3H)-isobenzofuranone

2-{2,5-Dimethoxy-4-[3-(2,2,2-trichloro-ethoxycarbonyl)-propyl]-benzoyl}-3-methoxy-benzoic acid methyl ester

dimethyl 3-methoxyphthalate

Refernces

• 1、 -. "Regiospecific synthesis of anthracyclinone compounds such as daunomycinone". . . Retrieved 2008/06/13.