1-(2-Chlorophenyl)-3-cyclohexylurea

Base Information

• Chemical Name: 1-(2-Chlorophenyl)-3-cyclohexylurea
• CAS No.: 72802-44-9
• Molecular Formula: C13H17 Cl N2 O
• Molecular Weight: 252.7399
• NSC Number: 204146
• DSSTox Substance ID: DTXSID70308449
• Wikidata: Q82056339
• Mol file: 72802-44-9.mol

Synonyms:1-(2-chlorophenyl)-3-cyclohexylurea;72802-44-9;NSC 204146;NSC204146;Cambridge id 5360713;SCHEMBL11336178;DTXSID70308449;AKOS002936036;N-(2-chlorophenyl)-N'-cyclohexylurea;NSC-204146;AB00082958-01;SR-01000207021;SR-01000207021-1

Chemical Property of 1-(2-Chlorophenyl)-3-cyclohexylurea

Chemical Property:

• Vapor Pressure: 2.88E-05mmHg at 25°C
• Boiling Point: 356.7°Cat760mmHg
• Flash Point: 169.5°C
• Density: 1.2g/cm³
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 252.1029409
• Heavy Atom Count: 17
• Complexity: 254

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(CC1)NC(=O)NC2=CC=CC=C2Cl

Technology Process of 1-(2-Chlorophenyl)-3-cyclohexylurea

There total 1 articles about 1-(2-Chlorophenyl)-3-cyclohexylurea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

o-chlorobenzoyl azide (49747-51-5) + cyclohexylamine (108-91-8,157973-60-9) → 1-(2-chlorophenyl)-3-cyclohexylurea (72802-44-9)

Guidance literature:

With benzene;

Reference yield: 92.0%

2,2,2-trifluoroethyl(2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate + 1-(2-chlorophenyl)-3-cyclohexylurea (72802-44-9) → C15H18ClF3N2O

Guidance literature:

1-(2-chlorophenyl)-3-cyclohexylurea; With palladium diacetate; trifluoroacetic acid; In dichloromethane; for 0.0166667h;

2,2,2-trifluoroethyl(2,4,6-trimethylphenyl)iodonium trifluoromethanesulfonate; In dichloromethane; at 25 ℃; for 3h; regioselective reaction;

DOI:10.1002/adsc.201601136

upstream raw materials:

o-chlorobenzoyl azide

cyclohexylamine