Technology Process of Nimbiol
There total 15 articles about Nimbiol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium hydroxide;
In
methanol;
DOI:10.1039/a708795k
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 50 percent / HI / benzene / 6 h / 85 °C
2: 90 percent / SnCl4 / 0.7 h / 85 °C
3: 91 percent / urea-hydrogen peroxide; TFAA / 24 h / 20 °C
4: 65 percent / Na2CrO4; Ac2O / acetic acid / 2 h / 65 °C
5: 98 percent / K2CO3 / methanol; H2O / 0.7 h / 20 °C
With
sodium chromate(VI); urea-hydrogen peroxide; hydrogen iodide; acetic anhydride; potassium carbonate; trifluoroacetic anhydride;
tin(IV) chloride;
In
methanol; water; acetic acid; benzene;
2: Friedel-Crafts acylation / 3: Baeyer-Villiger oxidation;
DOI:10.1055/s-2007-982533
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 81 percent / KMO4; MgSO4
2: 50 percent / HI / benzene / 6 h / 85 °C
3: 90 percent / SnCl4 / 0.7 h / 85 °C
4: 91 percent / urea-hydrogen peroxide; TFAA / 24 h / 20 °C
5: 65 percent / Na2CrO4; Ac2O / acetic acid / 2 h / 65 °C
6: 98 percent / K2CO3 / methanol; H2O / 0.7 h / 20 °C
With
sodium chromate(VI); urea-hydrogen peroxide; hydrogen iodide; acetic anhydride; magnesium sulfate; potassium carbonate; trifluoroacetic anhydride;
tin(IV) chloride;
In
methanol; water; acetic acid; benzene;
3: Friedel-Crafts acylation / 4: Baeyer-Villiger oxidation;
DOI:10.1055/s-2007-982533