1,1-BIS(METHYLTHIO)ETHYLENE

Base Information

• Chemical Name: 1,1-BIS(METHYLTHIO)ETHYLENE
• CAS No.: 51102-74-0
• Molecular Formula: C4H8 S2
• Molecular Weight: 120.24
• Mol file: 51102-74-0.mol

Synonyms:1,1-Bis(methylthio)ethene;1,1-Bis(methylthio)ethylene

Chemical Property of 1,1-BIS(METHYLTHIO)ETHYLENE

Chemical Property:

• Vapor Pressure: 0.82mmHg at 25°C
• Refractive Index: 1.5570-1.5640
• Boiling Point: 188.6°Cat760mmHg
• Flash Point: 70.4°C
• PSA: 50.60000
• Density: 1.024g/cm³
• LogP: 2.18360
• Storage Temp.: 0-10°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,1-Bis(methylthio)ethylene ^*data from reagent suppliers

Safty Information:

• Statements: 10
• Safety Statements: 16

MSDS Files:

Useful:

Technology Process of 1,1-BIS(METHYLTHIO)ETHYLENE

There total 19 articles about 1,1-BIS(METHYLTHIO)ETHYLENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

methyl dithioacetate (2168-84-5) + dimethyl sulfate (77-78-1) → 1,1-bis(methylthio)ethylene (51102-74-0)

Guidance literature:

With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃;

DOI:10.1021/jo00314a050

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + methylmagnesium bromide (75-16-1) + dimethyl sulfate (77-78-1) → 1,1-bis(methylthio)ethylene (51102-74-0)

Guidance literature:

carbon disulfide; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 40 ℃; for 2.75h;

With lithium diisopropyl amide; In tetrahydrofuran; diethyl ether; n-heptane; ethylbenzene; at -60 ℃; for 3.25h;

dimethyl sulfate; In tetrahydrofuran; diethyl ether; n-heptane; ethylbenzene; at -60 - 20 ℃; for 18.9167h;

Reference yield:

dithioacetic acid (594-03-6) + dimethyl sulfate (77-78-1) → 1,1-bis(methylthio)ethylene (51102-74-0)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; at -78 ℃; Yield given;

DOI:10.1021/jo00314a050

upstream raw materials:

3,3-bis(methylthio)acrylic acid

formaldehyd

dimethyl bis(methylmercapto)methylphosphonate

bis(methylsulfanyl)trimethylsilylmethane

Downstream raw materials:

5,5-bis-methylsulfanyl-8-(p-toluenesulfonyl)-1,5,6,7-tetrahydro-oxazolo[3,4-a]pyridin-3-one

(+)-1-benzoyl-5,5-bis(methylthio)-3-(2-phenylethyl)pyrazolidine

Refernces

• 1、 -. "Nitrogen containing heteroaromatics as factor Xa inhibitors". . . Retrieved 2008/06/13.
• 2、 Hartke, Klaus,Rettberg, Norbert,Dutta, Dinah,Gerber, Hans-Dieter. "Dithio and Thiono Esters, 59. - Reactions of Aliphatic Dithio Acid Dianions with Carbon Disulfide". . p. 1081 - 1090. Retrieved 2007/10/02.